Mass spectrometry and mass-selective detection in chromatography

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

An overview of chromatography-mass spectrometry coupling is presented here, focussing mainly on possibilities offered by this detection technique. GC-MS and HPLC-MS are the two most often used variants, which have quite different characteristics. Various mass-spectrometric possibilities are briefly discussed: ionization techniques, determination of elemental formulas, structural information and the question of sensitivity and selectivity. Options for mass-spectrometric instrumentation and applications of tandem mass spectrometry are also mentioned.

Original languageEnglish
Pages (from-to)227-236
Number of pages10
JournalJournal of Chromatography A
Volume921
Issue number2
DOIs
Publication statusPublished - Jul 6 2001

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Tandem Mass Spectrometry
Chromatography
Mass spectrometry
Mass Spectrometry
High Pressure Liquid Chromatography
Ionization

Keywords

  • Detection, GC
  • Detection, LC
  • Mass spectrometry

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Mass spectrometry and mass-selective detection in chromatography. / Vékey, K.

In: Journal of Chromatography A, Vol. 921, No. 2, 06.07.2001, p. 227-236.

Research output: Contribution to journalArticle

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