Three genes hemE, hemF, hemG taking part in the porphyrin biosynthesis of Bacillus subtilis were mapped by two- and tree-factor transduction crosses. The gene hemE determines uroporphyrinogen decarboxylase (EC 126.96.36.199) the gene hemF coproporyphyrinogen oxidase (EC 188.8.131.52) and the gene hemG, ferrochelatase (EC 4.99. 1.1) enzymes. The loci hemE, hemF, hemG, are not linked to hemA locus and located near the argC and metD loci.
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