Esophageal cancer including squamosus cell and adenocarcinoma is a realatively uncommon malignant condition worldwide with respect to prognosis. The main etiological factors that have been associated with the disease are smoking, alcohol consumption, chronic irritation, history of radiotherapy to the mediastinum and Barrett metaplasia. During the past three decades the incidence and the associated mortality rate have increased, while the histologic pattern has changed significantly. The diagnostic and staging accuracy in esophageal cancer cases has been improving by the introduction of new various image processing technologies. In the management of esophageal carcinoma still surgery plays the most important role. Adjuvant therapies include preoperative or postoperative radiotherapy or chemotherapy, and preoperative combined chemo- and radiotherapy. Recent advances in the diagnosis, staging, and treatment of this neoplastic condition have led to small but significant improvements in survival. These new observations serve as the focus of this review.
|Translated title of the contribution||Malignancies of the oesophagus: Pathogenesis, diagnosis and treatment (review)|
|Number of pages||10|
|Publication status||Published - Dec 1 2006|
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