The nature and contribution to biological function of macromolecular fluctuations are discussed at phenomenological level. The protein fluctuations in enzyme function, the lateral and rotational mobility of intramembrane proteins are treated as essential traits of these macromolecular assemblies responsible for their biological behavior, regulation and function. These considerations lead us to propose new experimental possibilities for studying regulatory processes involving membrane receptors or transcription factors, including those related to oncogenes.
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Condensed Matter Physics
- Physical and Theoretical Chemistry
- Materials Chemistry