Macromolecular fluctuation and biological function

Research output: Contribution to journalArticle

Abstract

The nature and contribution to biological function of macromolecular fluctuations are discussed at phenomenological level. The protein fluctuations in enzyme function, the lateral and rotational mobility of intramembrane proteins are treated as essential traits of these macromolecular assemblies responsible for their biological behavior, regulation and function. These considerations lead us to propose new experimental possibilities for studying regulatory processes involving membrane receptors or transcription factors, including those related to oncogenes.

Original languageEnglish
Pages (from-to)59-70
Number of pages12
JournalJournal of Molecular Liquids
Volume42
Issue numberC
DOIs
Publication statusPublished - 1989

Fingerprint

oncogenes
proteins
Proteins
Transcription factors
assemblies
enzymes
Transcription Factors
Enzymes
membranes
Membranes

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Atomic and Molecular Physics, and Optics

Cite this

Macromolecular fluctuation and biological function. / Szabó, G.; Somogyi, B.; Damjanovich, S.

In: Journal of Molecular Liquids, Vol. 42, No. C, 1989, p. 59-70.

Research output: Contribution to journalArticle

@article{42cdc9c1ebca472199d7f3150b57f8b2,
title = "Macromolecular fluctuation and biological function",
abstract = "The nature and contribution to biological function of macromolecular fluctuations are discussed at phenomenological level. The protein fluctuations in enzyme function, the lateral and rotational mobility of intramembrane proteins are treated as essential traits of these macromolecular assemblies responsible for their biological behavior, regulation and function. These considerations lead us to propose new experimental possibilities for studying regulatory processes involving membrane receptors or transcription factors, including those related to oncogenes.",
author = "G. Szab{\'o} and B. Somogyi and S. Damjanovich",
year = "1989",
doi = "10.1016/0167-7322(89)80025-X",
language = "English",
volume = "42",
pages = "59--70",
journal = "Journal of Molecular Liquids",
issn = "0167-7322",
publisher = "Elsevier",
number = "C",

}

TY - JOUR

T1 - Macromolecular fluctuation and biological function

AU - Szabó, G.

AU - Somogyi, B.

AU - Damjanovich, S.

PY - 1989

Y1 - 1989

N2 - The nature and contribution to biological function of macromolecular fluctuations are discussed at phenomenological level. The protein fluctuations in enzyme function, the lateral and rotational mobility of intramembrane proteins are treated as essential traits of these macromolecular assemblies responsible for their biological behavior, regulation and function. These considerations lead us to propose new experimental possibilities for studying regulatory processes involving membrane receptors or transcription factors, including those related to oncogenes.

AB - The nature and contribution to biological function of macromolecular fluctuations are discussed at phenomenological level. The protein fluctuations in enzyme function, the lateral and rotational mobility of intramembrane proteins are treated as essential traits of these macromolecular assemblies responsible for their biological behavior, regulation and function. These considerations lead us to propose new experimental possibilities for studying regulatory processes involving membrane receptors or transcription factors, including those related to oncogenes.

UR - http://www.scopus.com/inward/record.url?scp=45349110153&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=45349110153&partnerID=8YFLogxK

U2 - 10.1016/0167-7322(89)80025-X

DO - 10.1016/0167-7322(89)80025-X

M3 - Article

AN - SCOPUS:45349110153

VL - 42

SP - 59

EP - 70

JO - Journal of Molecular Liquids

JF - Journal of Molecular Liquids

SN - 0167-7322

IS - C

ER -