Lysosomal enzymes in sera and granulocytes of patients with chronic liver diseases

J. Fehér, H. Toncsev, E. Fehér, A. Kiss, A. Vasady

Research output: Contribution to journalArticle

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Abstract

The authors have measured the activity of acid phosphatase, β-glucuronidase and cathepsin-D in the sera of patients with different liver diseases, and the activity of β-glucuronidase in granulocytes and the rate of its release. Using the method for the release of β-glucuronidase from the granulocytes they drew conclusion to the degree of the membrane-damage occurring in the different liver diseases. They provided that in the sera of patients with different liver diseases the increase in the activity of the acid phosphatase and the β-glucuronidase is different. According to their in vitro studies the decrease in the β-glucuronidase activity measured in the granulocytes, and the release of enzyme is in connection with the type of liver disease and with the different degree of lysosomal membrane alteration.

Original languageEnglish
Pages (from-to)31-37
Number of pages7
JournalInternational Journal of Tissue Reactions
Volume3
Issue number1
Publication statusPublished - 1981

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Glucuronidase
Granulocytes
Liver Diseases
Chronic Disease
Enzymes
Serum
Acid Phosphatase
Cathepsin D
Membranes

ASJC Scopus subject areas

  • Physiology
  • Cell Biology

Cite this

Lysosomal enzymes in sera and granulocytes of patients with chronic liver diseases. / Fehér, J.; Toncsev, H.; Fehér, E.; Kiss, A.; Vasady, A.

In: International Journal of Tissue Reactions, Vol. 3, No. 1, 1981, p. 31-37.

Research output: Contribution to journalArticle

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