Lymphoepithelioma-like carcinoma of the breast: not Epstein-Barr virus-, but human papilloma virus-positive

J. Kulka, I. Kovalszky, Egon Svastics, Mária Berta, T. Füle

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

Lymphoepithelioma-like carcinoma of the breast is a rare tumor, with fewer than 20 cases documented in the literature. None of the published cases was Epstein-Barr virus positive, and our case was also Epstein-Barr virus negative. However, in our case, human papilloma virus (HPV) types 18 and 33 DNA could be demonstrated within the tumor tissue. Many years previously, the patient underwent hysterectomy for cervical carcinoma in situ which showed the presence of HPV-33. To the best of our knowledge, this is the first report on lymphoepithelioma-like carcinoma of the breast where high-risk HPV infection may be suggested as an etiological factor in a patient with a previous history of cervical carcinoma in situ.

Original languageEnglish
Pages (from-to)298-301
Number of pages4
JournalHuman Pathology
Volume39
Issue number2
DOIs
Publication statusPublished - Feb 2008

Fingerprint

Papillomaviridae
Human Herpesvirus 4
Carcinoma in Situ
Breast Neoplasms
Virus Diseases
Hysterectomy
Neoplasms
DNA

Keywords

  • Breast
  • HPV
  • Lymphoepithelioma-like carcinoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Lymphoepithelioma-like carcinoma of the breast : not Epstein-Barr virus-, but human papilloma virus-positive. / Kulka, J.; Kovalszky, I.; Svastics, Egon; Berta, Mária; Füle, T.

In: Human Pathology, Vol. 39, No. 2, 02.2008, p. 298-301.

Research output: Contribution to journalArticle

@article{af1676353f23464cb7f02fd6f4662842,
title = "Lymphoepithelioma-like carcinoma of the breast: not Epstein-Barr virus-, but human papilloma virus-positive",
abstract = "Lymphoepithelioma-like carcinoma of the breast is a rare tumor, with fewer than 20 cases documented in the literature. None of the published cases was Epstein-Barr virus positive, and our case was also Epstein-Barr virus negative. However, in our case, human papilloma virus (HPV) types 18 and 33 DNA could be demonstrated within the tumor tissue. Many years previously, the patient underwent hysterectomy for cervical carcinoma in situ which showed the presence of HPV-33. To the best of our knowledge, this is the first report on lymphoepithelioma-like carcinoma of the breast where high-risk HPV infection may be suggested as an etiological factor in a patient with a previous history of cervical carcinoma in situ.",
keywords = "Breast, HPV, Lymphoepithelioma-like carcinoma",
author = "J. Kulka and I. Kovalszky and Egon Svastics and M{\'a}ria Berta and T. F{\"u}le",
year = "2008",
month = "2",
doi = "10.1016/j.humpath.2007.08.006",
language = "English",
volume = "39",
pages = "298--301",
journal = "Human Pathology",
issn = "0046-8177",
publisher = "W.B. Saunders Ltd",
number = "2",

}

TY - JOUR

T1 - Lymphoepithelioma-like carcinoma of the breast

T2 - not Epstein-Barr virus-, but human papilloma virus-positive

AU - Kulka, J.

AU - Kovalszky, I.

AU - Svastics, Egon

AU - Berta, Mária

AU - Füle, T.

PY - 2008/2

Y1 - 2008/2

N2 - Lymphoepithelioma-like carcinoma of the breast is a rare tumor, with fewer than 20 cases documented in the literature. None of the published cases was Epstein-Barr virus positive, and our case was also Epstein-Barr virus negative. However, in our case, human papilloma virus (HPV) types 18 and 33 DNA could be demonstrated within the tumor tissue. Many years previously, the patient underwent hysterectomy for cervical carcinoma in situ which showed the presence of HPV-33. To the best of our knowledge, this is the first report on lymphoepithelioma-like carcinoma of the breast where high-risk HPV infection may be suggested as an etiological factor in a patient with a previous history of cervical carcinoma in situ.

AB - Lymphoepithelioma-like carcinoma of the breast is a rare tumor, with fewer than 20 cases documented in the literature. None of the published cases was Epstein-Barr virus positive, and our case was also Epstein-Barr virus negative. However, in our case, human papilloma virus (HPV) types 18 and 33 DNA could be demonstrated within the tumor tissue. Many years previously, the patient underwent hysterectomy for cervical carcinoma in situ which showed the presence of HPV-33. To the best of our knowledge, this is the first report on lymphoepithelioma-like carcinoma of the breast where high-risk HPV infection may be suggested as an etiological factor in a patient with a previous history of cervical carcinoma in situ.

KW - Breast

KW - HPV

KW - Lymphoepithelioma-like carcinoma

UR - http://www.scopus.com/inward/record.url?scp=38349057310&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38349057310&partnerID=8YFLogxK

U2 - 10.1016/j.humpath.2007.08.006

DO - 10.1016/j.humpath.2007.08.006

M3 - Article

C2 - 18206498

AN - SCOPUS:38349057310

VL - 39

SP - 298

EP - 301

JO - Human Pathology

JF - Human Pathology

SN - 0046-8177

IS - 2

ER -