Lung cancer risk among hairdressers: A pooled analysis of case-control studies conducted between 1985 and 2010

Ann C. Olsson, Yiwen Xu, Joachim Schüz, Jelle Vlaanderen, Hans Kromhout, Roel Vermeulen, Susan Peters, Isabelle Stücker, Florence Guida, Irene Brüske, Heinz Erich Wichmann, Dario Consonni, Maria Teresa Landi, Neil Caporaso, Lap Ah Tse, Ignatius Tak Sun Yu, Jack Siemiatycki, Lesley Richardson, Dario Mirabelli, Lorenzo RichiardiLorenzo Simonato, Per Gustavsson, Nils Plato, Karl Heinz Jöckel, Wolfgang Ahrens, Hermann Pohlabeln, Adonina Tardón, David Zaridze, Michael W. Marcus, Andrea't Mannetje, Neil Pearce, John McLaughlin, Paul Demers, Neonila Szeszenia-Dabrowska, Jolanta Lissowska, P. Rudnai, Eleonora Fabianova, Rodica Stanescu Dumitru, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Paolo Boffetta, Cristina Fortes, Bas Bueno-De-Mesquita, Benjamin Kendzia, Thomas Behrens, Beate Pesch, Thomas Brüning, Kurt Straif

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Increased lung cancer risks among hairdressers were observed in large registry-based cohort studies from Scandinavia, but these studies could not adjust for smoking. Our objective was to evaluate the lung cancer risk among hairdressers while adjusting for smoking and other confounders in a pooled database of 16 case-control studies conducted in Europe, Canada, China, and New Zealand between 1985 and 2010 (the Pooled Analysis of Case-Control Studies on the Joint Effects of Occupational Carcinogens in the Development of Lung Cancer). Lifetime occupational and smoking information was collected through interviews with 19,369 cases of lung cancer and 23,674 matched population or hospital controls. Overall, 170 cases and 167 controls had ever worked as hairdresser or barber. The odds ratios for lung cancer in women were 1.65 (95% confidence interval (CI): 1.16, 2.35) without adjustment for smoking and 1.12 (95% CI: 0.75, 1.68) with adjustment for smoking; however, women employed before 1954 also experienced an increased lung cancer risk after adjustment for smoking (odds ratio = 2.66, 95% CI: 1.09, 6.47). The odds ratios in male hairdressers/barbers were generally not elevated, except for an increased odds ratio for adenocarcinoma in long-term barbers (odds ratio = 2.20, 95% CI: 1.02, 4.77). Our results suggest that the increased lung cancer risks among hairdressers are due to their smoking behavior; single elevated risk estimates should be interpreted with caution and need replication in other studies.

Original languageEnglish
Pages (from-to)1355-1365
Number of pages11
JournalAmerican Journal of Epidemiology
Volume178
Issue number9
DOIs
Publication statusPublished - Nov 1 2013

Fingerprint

Case-Control Studies
Lung Neoplasms
Smoking
Odds Ratio
Confidence Intervals
Scandinavian and Nordic Countries
Risk Adjustment
New Zealand
Carcinogens
Canada
Registries
China
Adenocarcinoma
Cohort Studies
Databases
Interviews
Population

Keywords

  • Case-control studies
  • Hair bleaching agents
  • Hair color
  • Lung neoplasms
  • Occupational exposure

ASJC Scopus subject areas

  • Epidemiology

Cite this

Olsson, A. C., Xu, Y., Schüz, J., Vlaanderen, J., Kromhout, H., Vermeulen, R., ... Straif, K. (2013). Lung cancer risk among hairdressers: A pooled analysis of case-control studies conducted between 1985 and 2010. American Journal of Epidemiology, 178(9), 1355-1365. https://doi.org/10.1093/aje/kwt119

Lung cancer risk among hairdressers : A pooled analysis of case-control studies conducted between 1985 and 2010. / Olsson, Ann C.; Xu, Yiwen; Schüz, Joachim; Vlaanderen, Jelle; Kromhout, Hans; Vermeulen, Roel; Peters, Susan; Stücker, Isabelle; Guida, Florence; Brüske, Irene; Wichmann, Heinz Erich; Consonni, Dario; Landi, Maria Teresa; Caporaso, Neil; Tse, Lap Ah; Yu, Ignatius Tak Sun; Siemiatycki, Jack; Richardson, Lesley; Mirabelli, Dario; Richiardi, Lorenzo; Simonato, Lorenzo; Gustavsson, Per; Plato, Nils; Jöckel, Karl Heinz; Ahrens, Wolfgang; Pohlabeln, Hermann; Tardón, Adonina; Zaridze, David; Marcus, Michael W.; Mannetje, Andrea't; Pearce, Neil; McLaughlin, John; Demers, Paul; Szeszenia-Dabrowska, Neonila; Lissowska, Jolanta; Rudnai, P.; Fabianova, Eleonora; Dumitru, Rodica Stanescu; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Boffetta, Paolo; Fortes, Cristina; Bueno-De-Mesquita, Bas; Kendzia, Benjamin; Behrens, Thomas; Pesch, Beate; Brüning, Thomas; Straif, Kurt.

In: American Journal of Epidemiology, Vol. 178, No. 9, 01.11.2013, p. 1355-1365.

Research output: Contribution to journalArticle

Olsson, AC, Xu, Y, Schüz, J, Vlaanderen, J, Kromhout, H, Vermeulen, R, Peters, S, Stücker, I, Guida, F, Brüske, I, Wichmann, HE, Consonni, D, Landi, MT, Caporaso, N, Tse, LA, Yu, ITS, Siemiatycki, J, Richardson, L, Mirabelli, D, Richiardi, L, Simonato, L, Gustavsson, P, Plato, N, Jöckel, KH, Ahrens, W, Pohlabeln, H, Tardón, A, Zaridze, D, Marcus, MW, Mannetje, A, Pearce, N, McLaughlin, J, Demers, P, Szeszenia-Dabrowska, N, Lissowska, J, Rudnai, P, Fabianova, E, Dumitru, RS, Bencko, V, Foretova, L, Janout, V, Boffetta, P, Fortes, C, Bueno-De-Mesquita, B, Kendzia, B, Behrens, T, Pesch, B, Brüning, T & Straif, K 2013, 'Lung cancer risk among hairdressers: A pooled analysis of case-control studies conducted between 1985 and 2010', American Journal of Epidemiology, vol. 178, no. 9, pp. 1355-1365. https://doi.org/10.1093/aje/kwt119
Olsson, Ann C. ; Xu, Yiwen ; Schüz, Joachim ; Vlaanderen, Jelle ; Kromhout, Hans ; Vermeulen, Roel ; Peters, Susan ; Stücker, Isabelle ; Guida, Florence ; Brüske, Irene ; Wichmann, Heinz Erich ; Consonni, Dario ; Landi, Maria Teresa ; Caporaso, Neil ; Tse, Lap Ah ; Yu, Ignatius Tak Sun ; Siemiatycki, Jack ; Richardson, Lesley ; Mirabelli, Dario ; Richiardi, Lorenzo ; Simonato, Lorenzo ; Gustavsson, Per ; Plato, Nils ; Jöckel, Karl Heinz ; Ahrens, Wolfgang ; Pohlabeln, Hermann ; Tardón, Adonina ; Zaridze, David ; Marcus, Michael W. ; Mannetje, Andrea't ; Pearce, Neil ; McLaughlin, John ; Demers, Paul ; Szeszenia-Dabrowska, Neonila ; Lissowska, Jolanta ; Rudnai, P. ; Fabianova, Eleonora ; Dumitru, Rodica Stanescu ; Bencko, Vladimir ; Foretova, Lenka ; Janout, Vladimir ; Boffetta, Paolo ; Fortes, Cristina ; Bueno-De-Mesquita, Bas ; Kendzia, Benjamin ; Behrens, Thomas ; Pesch, Beate ; Brüning, Thomas ; Straif, Kurt. / Lung cancer risk among hairdressers : A pooled analysis of case-control studies conducted between 1985 and 2010. In: American Journal of Epidemiology. 2013 ; Vol. 178, No. 9. pp. 1355-1365.
@article{4372e375a25e440b8d698807ab6f45c1,
title = "Lung cancer risk among hairdressers: A pooled analysis of case-control studies conducted between 1985 and 2010",
abstract = "Increased lung cancer risks among hairdressers were observed in large registry-based cohort studies from Scandinavia, but these studies could not adjust for smoking. Our objective was to evaluate the lung cancer risk among hairdressers while adjusting for smoking and other confounders in a pooled database of 16 case-control studies conducted in Europe, Canada, China, and New Zealand between 1985 and 2010 (the Pooled Analysis of Case-Control Studies on the Joint Effects of Occupational Carcinogens in the Development of Lung Cancer). Lifetime occupational and smoking information was collected through interviews with 19,369 cases of lung cancer and 23,674 matched population or hospital controls. Overall, 170 cases and 167 controls had ever worked as hairdresser or barber. The odds ratios for lung cancer in women were 1.65 (95{\%} confidence interval (CI): 1.16, 2.35) without adjustment for smoking and 1.12 (95{\%} CI: 0.75, 1.68) with adjustment for smoking; however, women employed before 1954 also experienced an increased lung cancer risk after adjustment for smoking (odds ratio = 2.66, 95{\%} CI: 1.09, 6.47). The odds ratios in male hairdressers/barbers were generally not elevated, except for an increased odds ratio for adenocarcinoma in long-term barbers (odds ratio = 2.20, 95{\%} CI: 1.02, 4.77). Our results suggest that the increased lung cancer risks among hairdressers are due to their smoking behavior; single elevated risk estimates should be interpreted with caution and need replication in other studies.",
keywords = "Case-control studies, Hair bleaching agents, Hair color, Lung neoplasms, Occupational exposure",
author = "Olsson, {Ann C.} and Yiwen Xu and Joachim Sch{\"u}z and Jelle Vlaanderen and Hans Kromhout and Roel Vermeulen and Susan Peters and Isabelle St{\"u}cker and Florence Guida and Irene Br{\"u}ske and Wichmann, {Heinz Erich} and Dario Consonni and Landi, {Maria Teresa} and Neil Caporaso and Tse, {Lap Ah} and Yu, {Ignatius Tak Sun} and Jack Siemiatycki and Lesley Richardson and Dario Mirabelli and Lorenzo Richiardi and Lorenzo Simonato and Per Gustavsson and Nils Plato and J{\"o}ckel, {Karl Heinz} and Wolfgang Ahrens and Hermann Pohlabeln and Adonina Tard{\'o}n and David Zaridze and Marcus, {Michael W.} and Andrea't Mannetje and Neil Pearce and John McLaughlin and Paul Demers and Neonila Szeszenia-Dabrowska and Jolanta Lissowska and P. Rudnai and Eleonora Fabianova and Dumitru, {Rodica Stanescu} and Vladimir Bencko and Lenka Foretova and Vladimir Janout and Paolo Boffetta and Cristina Fortes and Bas Bueno-De-Mesquita and Benjamin Kendzia and Thomas Behrens and Beate Pesch and Thomas Br{\"u}ning and Kurt Straif",
year = "2013",
month = "11",
day = "1",
doi = "10.1093/aje/kwt119",
language = "English",
volume = "178",
pages = "1355--1365",
journal = "American Journal of Epidemiology",
issn = "0002-9262",
publisher = "Oxford University Press",
number = "9",

}

TY - JOUR

T1 - Lung cancer risk among hairdressers

T2 - A pooled analysis of case-control studies conducted between 1985 and 2010

AU - Olsson, Ann C.

AU - Xu, Yiwen

AU - Schüz, Joachim

AU - Vlaanderen, Jelle

AU - Kromhout, Hans

AU - Vermeulen, Roel

AU - Peters, Susan

AU - Stücker, Isabelle

AU - Guida, Florence

AU - Brüske, Irene

AU - Wichmann, Heinz Erich

AU - Consonni, Dario

AU - Landi, Maria Teresa

AU - Caporaso, Neil

AU - Tse, Lap Ah

AU - Yu, Ignatius Tak Sun

AU - Siemiatycki, Jack

AU - Richardson, Lesley

AU - Mirabelli, Dario

AU - Richiardi, Lorenzo

AU - Simonato, Lorenzo

AU - Gustavsson, Per

AU - Plato, Nils

AU - Jöckel, Karl Heinz

AU - Ahrens, Wolfgang

AU - Pohlabeln, Hermann

AU - Tardón, Adonina

AU - Zaridze, David

AU - Marcus, Michael W.

AU - Mannetje, Andrea't

AU - Pearce, Neil

AU - McLaughlin, John

AU - Demers, Paul

AU - Szeszenia-Dabrowska, Neonila

AU - Lissowska, Jolanta

AU - Rudnai, P.

AU - Fabianova, Eleonora

AU - Dumitru, Rodica Stanescu

AU - Bencko, Vladimir

AU - Foretova, Lenka

AU - Janout, Vladimir

AU - Boffetta, Paolo

AU - Fortes, Cristina

AU - Bueno-De-Mesquita, Bas

AU - Kendzia, Benjamin

AU - Behrens, Thomas

AU - Pesch, Beate

AU - Brüning, Thomas

AU - Straif, Kurt

PY - 2013/11/1

Y1 - 2013/11/1

N2 - Increased lung cancer risks among hairdressers were observed in large registry-based cohort studies from Scandinavia, but these studies could not adjust for smoking. Our objective was to evaluate the lung cancer risk among hairdressers while adjusting for smoking and other confounders in a pooled database of 16 case-control studies conducted in Europe, Canada, China, and New Zealand between 1985 and 2010 (the Pooled Analysis of Case-Control Studies on the Joint Effects of Occupational Carcinogens in the Development of Lung Cancer). Lifetime occupational and smoking information was collected through interviews with 19,369 cases of lung cancer and 23,674 matched population or hospital controls. Overall, 170 cases and 167 controls had ever worked as hairdresser or barber. The odds ratios for lung cancer in women were 1.65 (95% confidence interval (CI): 1.16, 2.35) without adjustment for smoking and 1.12 (95% CI: 0.75, 1.68) with adjustment for smoking; however, women employed before 1954 also experienced an increased lung cancer risk after adjustment for smoking (odds ratio = 2.66, 95% CI: 1.09, 6.47). The odds ratios in male hairdressers/barbers were generally not elevated, except for an increased odds ratio for adenocarcinoma in long-term barbers (odds ratio = 2.20, 95% CI: 1.02, 4.77). Our results suggest that the increased lung cancer risks among hairdressers are due to their smoking behavior; single elevated risk estimates should be interpreted with caution and need replication in other studies.

AB - Increased lung cancer risks among hairdressers were observed in large registry-based cohort studies from Scandinavia, but these studies could not adjust for smoking. Our objective was to evaluate the lung cancer risk among hairdressers while adjusting for smoking and other confounders in a pooled database of 16 case-control studies conducted in Europe, Canada, China, and New Zealand between 1985 and 2010 (the Pooled Analysis of Case-Control Studies on the Joint Effects of Occupational Carcinogens in the Development of Lung Cancer). Lifetime occupational and smoking information was collected through interviews with 19,369 cases of lung cancer and 23,674 matched population or hospital controls. Overall, 170 cases and 167 controls had ever worked as hairdresser or barber. The odds ratios for lung cancer in women were 1.65 (95% confidence interval (CI): 1.16, 2.35) without adjustment for smoking and 1.12 (95% CI: 0.75, 1.68) with adjustment for smoking; however, women employed before 1954 also experienced an increased lung cancer risk after adjustment for smoking (odds ratio = 2.66, 95% CI: 1.09, 6.47). The odds ratios in male hairdressers/barbers were generally not elevated, except for an increased odds ratio for adenocarcinoma in long-term barbers (odds ratio = 2.20, 95% CI: 1.02, 4.77). Our results suggest that the increased lung cancer risks among hairdressers are due to their smoking behavior; single elevated risk estimates should be interpreted with caution and need replication in other studies.

KW - Case-control studies

KW - Hair bleaching agents

KW - Hair color

KW - Lung neoplasms

KW - Occupational exposure

UR - http://www.scopus.com/inward/record.url?scp=84890062215&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84890062215&partnerID=8YFLogxK

U2 - 10.1093/aje/kwt119

DO - 10.1093/aje/kwt119

M3 - Article

C2 - 24068200

AN - SCOPUS:84890062215

VL - 178

SP - 1355

EP - 1365

JO - American Journal of Epidemiology

JF - American Journal of Epidemiology

SN - 0002-9262

IS - 9

ER -