Lung Cancer Risk Among Cooks When Accounting for Tobacco Smoking

A Pooled Analysis of Case-Control Studies From Europe, Canada, New Zealand, and China

Carolina Bigert, Per Gustavsson, Kurt Straif, Beate Pesch, Thomas Brüning, Benjamin Kendzia, Joachim Schüz, Isabelle Stücker, Florence Guida, Irene Brüske, Heinz Erich Wichmann, Angela C. Pesatori, Maria Teresa Landi, Neil Caporaso, Lap Ah Tse, Ignatius Tak Sun Yu, Jack Siemiatycki, Javier Pintos, Franco Merletti, Dario Mirabelli & 26 others Lorenzo Simonato, Karl Heinz Jöckel, Wolfgang Ahrens, Hermann Pohlabeln, Adonina Tardón, David Zaridze, John Field, Andrea 'T Mannetje, Neil Pearce, John McLaughlin, Paul Demers, Neonila Szeszenia-Dabrowska, Jolanta Lissowska, P. Rudnai, Eleonora Fabianova, Rodica Stanescu Dumitru, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Paolo Boffetta, Francesco Forastiere, Bas Bueno-De-Mesquita, Susan Peters, Roel Vermeulen, Hans Kromhout, Ann C. Olsson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

OBJECTIVES: To investigate the risk of lung cancer among cooks, while controlling for smoking habits. METHODS: We used data from the SYNERGY project including pooled information on lifetime work histories and smoking habits from 16 case-control studies conducted in Europe, Canada, New Zealand, and China. RESULTS: Before adjustment for smoking, we observed an increased risk of lung cancer in male cooks, but not in female cooks. After adjusting, there was no increased risk and no significant exposure-response relationship. Nevertheless, subgroup analyses highlighted some possible excess risks of squamous cell carcinoma and small cell carcinoma in female cooks. CONCLUSIONS: There is evidence that lung cancer risks among cooks may be confounded by smoking. After adjustment, cooks did not experience an increased risk of lung cancer overall. The subgroup analyses showing some excess risks among female cooks require cautious interpretation.

Original languageEnglish
Pages (from-to)202-209
Number of pages8
JournalJournal of Occupational and Environmental Medicine
Volume57
Issue number2
DOIs
Publication statusPublished - Feb 13 2015

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New Zealand
Canada
Case-Control Studies
China
Lung Neoplasms
Smoking
Habits
Social Adjustment
Small Cell Carcinoma
Squamous Cell Carcinoma

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Medicine(all)

Cite this

Lung Cancer Risk Among Cooks When Accounting for Tobacco Smoking : A Pooled Analysis of Case-Control Studies From Europe, Canada, New Zealand, and China. / Bigert, Carolina; Gustavsson, Per; Straif, Kurt; Pesch, Beate; Brüning, Thomas; Kendzia, Benjamin; Schüz, Joachim; Stücker, Isabelle; Guida, Florence; Brüske, Irene; Wichmann, Heinz Erich; Pesatori, Angela C.; Landi, Maria Teresa; Caporaso, Neil; Tse, Lap Ah; Yu, Ignatius Tak Sun; Siemiatycki, Jack; Pintos, Javier; Merletti, Franco; Mirabelli, Dario; Simonato, Lorenzo; Jöckel, Karl Heinz; Ahrens, Wolfgang; Pohlabeln, Hermann; Tardón, Adonina; Zaridze, David; Field, John; 'T Mannetje, Andrea; Pearce, Neil; McLaughlin, John; Demers, Paul; Szeszenia-Dabrowska, Neonila; Lissowska, Jolanta; Rudnai, P.; Fabianova, Eleonora; Stanescu Dumitru, Rodica; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Boffetta, Paolo; Forastiere, Francesco; Bueno-De-Mesquita, Bas; Peters, Susan; Vermeulen, Roel; Kromhout, Hans; Olsson, Ann C.

In: Journal of Occupational and Environmental Medicine, Vol. 57, No. 2, 13.02.2015, p. 202-209.

Research output: Contribution to journalArticle

Bigert, C, Gustavsson, P, Straif, K, Pesch, B, Brüning, T, Kendzia, B, Schüz, J, Stücker, I, Guida, F, Brüske, I, Wichmann, HE, Pesatori, AC, Landi, MT, Caporaso, N, Tse, LA, Yu, ITS, Siemiatycki, J, Pintos, J, Merletti, F, Mirabelli, D, Simonato, L, Jöckel, KH, Ahrens, W, Pohlabeln, H, Tardón, A, Zaridze, D, Field, J, 'T Mannetje, A, Pearce, N, McLaughlin, J, Demers, P, Szeszenia-Dabrowska, N, Lissowska, J, Rudnai, P, Fabianova, E, Stanescu Dumitru, R, Bencko, V, Foretova, L, Janout, V, Boffetta, P, Forastiere, F, Bueno-De-Mesquita, B, Peters, S, Vermeulen, R, Kromhout, H & Olsson, AC 2015, 'Lung Cancer Risk Among Cooks When Accounting for Tobacco Smoking: A Pooled Analysis of Case-Control Studies From Europe, Canada, New Zealand, and China', Journal of Occupational and Environmental Medicine, vol. 57, no. 2, pp. 202-209. https://doi.org/10.1097/JOM.0000000000000337
Bigert, Carolina ; Gustavsson, Per ; Straif, Kurt ; Pesch, Beate ; Brüning, Thomas ; Kendzia, Benjamin ; Schüz, Joachim ; Stücker, Isabelle ; Guida, Florence ; Brüske, Irene ; Wichmann, Heinz Erich ; Pesatori, Angela C. ; Landi, Maria Teresa ; Caporaso, Neil ; Tse, Lap Ah ; Yu, Ignatius Tak Sun ; Siemiatycki, Jack ; Pintos, Javier ; Merletti, Franco ; Mirabelli, Dario ; Simonato, Lorenzo ; Jöckel, Karl Heinz ; Ahrens, Wolfgang ; Pohlabeln, Hermann ; Tardón, Adonina ; Zaridze, David ; Field, John ; 'T Mannetje, Andrea ; Pearce, Neil ; McLaughlin, John ; Demers, Paul ; Szeszenia-Dabrowska, Neonila ; Lissowska, Jolanta ; Rudnai, P. ; Fabianova, Eleonora ; Stanescu Dumitru, Rodica ; Bencko, Vladimir ; Foretova, Lenka ; Janout, Vladimir ; Boffetta, Paolo ; Forastiere, Francesco ; Bueno-De-Mesquita, Bas ; Peters, Susan ; Vermeulen, Roel ; Kromhout, Hans ; Olsson, Ann C. / Lung Cancer Risk Among Cooks When Accounting for Tobacco Smoking : A Pooled Analysis of Case-Control Studies From Europe, Canada, New Zealand, and China. In: Journal of Occupational and Environmental Medicine. 2015 ; Vol. 57, No. 2. pp. 202-209.
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abstract = "OBJECTIVES: To investigate the risk of lung cancer among cooks, while controlling for smoking habits. METHODS: We used data from the SYNERGY project including pooled information on lifetime work histories and smoking habits from 16 case-control studies conducted in Europe, Canada, New Zealand, and China. RESULTS: Before adjustment for smoking, we observed an increased risk of lung cancer in male cooks, but not in female cooks. After adjusting, there was no increased risk and no significant exposure-response relationship. Nevertheless, subgroup analyses highlighted some possible excess risks of squamous cell carcinoma and small cell carcinoma in female cooks. CONCLUSIONS: There is evidence that lung cancer risks among cooks may be confounded by smoking. After adjustment, cooks did not experience an increased risk of lung cancer overall. The subgroup analyses showing some excess risks among female cooks require cautious interpretation.",
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AU - Bigert, Carolina

AU - Gustavsson, Per

AU - Straif, Kurt

AU - Pesch, Beate

AU - Brüning, Thomas

AU - Kendzia, Benjamin

AU - Schüz, Joachim

AU - Stücker, Isabelle

AU - Guida, Florence

AU - Brüske, Irene

AU - Wichmann, Heinz Erich

AU - Pesatori, Angela C.

AU - Landi, Maria Teresa

AU - Caporaso, Neil

AU - Tse, Lap Ah

AU - Yu, Ignatius Tak Sun

AU - Siemiatycki, Jack

AU - Pintos, Javier

AU - Merletti, Franco

AU - Mirabelli, Dario

AU - Simonato, Lorenzo

AU - Jöckel, Karl Heinz

AU - Ahrens, Wolfgang

AU - Pohlabeln, Hermann

AU - Tardón, Adonina

AU - Zaridze, David

AU - Field, John

AU - 'T Mannetje, Andrea

AU - Pearce, Neil

AU - McLaughlin, John

AU - Demers, Paul

AU - Szeszenia-Dabrowska, Neonila

AU - Lissowska, Jolanta

AU - Rudnai, P.

AU - Fabianova, Eleonora

AU - Stanescu Dumitru, Rodica

AU - Bencko, Vladimir

AU - Foretova, Lenka

AU - Janout, Vladimir

AU - Boffetta, Paolo

AU - Forastiere, Francesco

AU - Bueno-De-Mesquita, Bas

AU - Peters, Susan

AU - Vermeulen, Roel

AU - Kromhout, Hans

AU - Olsson, Ann C.

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AB - OBJECTIVES: To investigate the risk of lung cancer among cooks, while controlling for smoking habits. METHODS: We used data from the SYNERGY project including pooled information on lifetime work histories and smoking habits from 16 case-control studies conducted in Europe, Canada, New Zealand, and China. RESULTS: Before adjustment for smoking, we observed an increased risk of lung cancer in male cooks, but not in female cooks. After adjusting, there was no increased risk and no significant exposure-response relationship. Nevertheless, subgroup analyses highlighted some possible excess risks of squamous cell carcinoma and small cell carcinoma in female cooks. CONCLUSIONS: There is evidence that lung cancer risks among cooks may be confounded by smoking. After adjustment, cooks did not experience an increased risk of lung cancer overall. The subgroup analyses showing some excess risks among female cooks require cautious interpretation.

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