Lung cancer risk among bakers, pastrycooks and confectionary makers

The SYNERGY study

Thomas Behrens, Benjamin Kendzia, Tabea Treppmann, Ann Olsson, Karl Heinz Jöckel, Per Gustavsson, Hermann Pohlabeln, Wolfgang Ahrens, Irene Brüske, Hans Erich Wichmann, Franco Merletti, Dario Mirabelli, Lorenzo Richiardi, Lorenzo Simonato, David Zaridze, Neonila Szeszenia-Dabrowska, P. Rudnai, Jolanta Lissowska, Eleonora Fabianova, Adonina Tardón & 29 others John Field, Rodica Stanescu Dumitru, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Jack Siemiatycki, Marie Elise Parent, John McLaughlin, Paul Demers, Maria Teresa Landi, Neil Caporaso, Hans Kromhout, Roel Vermeulen, Susan Peters, Simone Benhamou, Isabelle Stücker, Florence Guida, Dario Consonni, Bas Bueno-de-Mesquita, Andrea T. Mannetje, Neil Pearce, Lap Ah Tse, Ignatius Tak Sun Yu, Nils Plato, Paolo Boffetta, Kurt Straif, Joachim Schüz, Beate Pesch, Thomas Brüning

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Introduction: Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries. Methods: Occupation in a baking-related job was identi fied from the subjects' job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status. Results: 19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95% CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared. Discussion: The findings from this study do not suggest increased lung cancer risks in baking-related professions.

Original languageEnglish
Pages (from-to)810-814
Number of pages5
JournalOccupational and Environmental Medicine
Volume70
Issue number11
DOIs
Publication statusPublished - Nov 2013

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Lung Neoplasms
Occupations
Smoking
Working Women
Occupational Exposure
Carcinogens
Logistic Models
Databases
Lung

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Behrens, T., Kendzia, B., Treppmann, T., Olsson, A., Jöckel, K. H., Gustavsson, P., ... Brüning, T. (2013). Lung cancer risk among bakers, pastrycooks and confectionary makers: The SYNERGY study. Occupational and Environmental Medicine, 70(11), 810-814. https://doi.org/10.1136/oemed-2013-101469

Lung cancer risk among bakers, pastrycooks and confectionary makers : The SYNERGY study. / Behrens, Thomas; Kendzia, Benjamin; Treppmann, Tabea; Olsson, Ann; Jöckel, Karl Heinz; Gustavsson, Per; Pohlabeln, Hermann; Ahrens, Wolfgang; Brüske, Irene; Wichmann, Hans Erich; Merletti, Franco; Mirabelli, Dario; Richiardi, Lorenzo; Simonato, Lorenzo; Zaridze, David; Szeszenia-Dabrowska, Neonila; Rudnai, P.; Lissowska, Jolanta; Fabianova, Eleonora; Tardón, Adonina; Field, John; Dumitru, Rodica Stanescu; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Siemiatycki, Jack; Parent, Marie Elise; McLaughlin, John; Demers, Paul; Landi, Maria Teresa; Caporaso, Neil; Kromhout, Hans; Vermeulen, Roel; Peters, Susan; Benhamou, Simone; Stücker, Isabelle; Guida, Florence; Consonni, Dario; Bueno-de-Mesquita, Bas; Mannetje, Andrea T.; Pearce, Neil; Tse, Lap Ah; Yu, Ignatius Tak Sun; Plato, Nils; Boffetta, Paolo; Straif, Kurt; Schüz, Joachim; Pesch, Beate; Brüning, Thomas.

In: Occupational and Environmental Medicine, Vol. 70, No. 11, 11.2013, p. 810-814.

Research output: Contribution to journalArticle

Behrens, T, Kendzia, B, Treppmann, T, Olsson, A, Jöckel, KH, Gustavsson, P, Pohlabeln, H, Ahrens, W, Brüske, I, Wichmann, HE, Merletti, F, Mirabelli, D, Richiardi, L, Simonato, L, Zaridze, D, Szeszenia-Dabrowska, N, Rudnai, P, Lissowska, J, Fabianova, E, Tardón, A, Field, J, Dumitru, RS, Bencko, V, Foretova, L, Janout, V, Siemiatycki, J, Parent, ME, McLaughlin, J, Demers, P, Landi, MT, Caporaso, N, Kromhout, H, Vermeulen, R, Peters, S, Benhamou, S, Stücker, I, Guida, F, Consonni, D, Bueno-de-Mesquita, B, Mannetje, AT, Pearce, N, Tse, LA, Yu, ITS, Plato, N, Boffetta, P, Straif, K, Schüz, J, Pesch, B & Brüning, T 2013, 'Lung cancer risk among bakers, pastrycooks and confectionary makers: The SYNERGY study', Occupational and Environmental Medicine, vol. 70, no. 11, pp. 810-814. https://doi.org/10.1136/oemed-2013-101469
Behrens, Thomas ; Kendzia, Benjamin ; Treppmann, Tabea ; Olsson, Ann ; Jöckel, Karl Heinz ; Gustavsson, Per ; Pohlabeln, Hermann ; Ahrens, Wolfgang ; Brüske, Irene ; Wichmann, Hans Erich ; Merletti, Franco ; Mirabelli, Dario ; Richiardi, Lorenzo ; Simonato, Lorenzo ; Zaridze, David ; Szeszenia-Dabrowska, Neonila ; Rudnai, P. ; Lissowska, Jolanta ; Fabianova, Eleonora ; Tardón, Adonina ; Field, John ; Dumitru, Rodica Stanescu ; Bencko, Vladimir ; Foretova, Lenka ; Janout, Vladimir ; Siemiatycki, Jack ; Parent, Marie Elise ; McLaughlin, John ; Demers, Paul ; Landi, Maria Teresa ; Caporaso, Neil ; Kromhout, Hans ; Vermeulen, Roel ; Peters, Susan ; Benhamou, Simone ; Stücker, Isabelle ; Guida, Florence ; Consonni, Dario ; Bueno-de-Mesquita, Bas ; Mannetje, Andrea T. ; Pearce, Neil ; Tse, Lap Ah ; Yu, Ignatius Tak Sun ; Plato, Nils ; Boffetta, Paolo ; Straif, Kurt ; Schüz, Joachim ; Pesch, Beate ; Brüning, Thomas. / Lung cancer risk among bakers, pastrycooks and confectionary makers : The SYNERGY study. In: Occupational and Environmental Medicine. 2013 ; Vol. 70, No. 11. pp. 810-814.
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abstract = "Introduction: Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries. Methods: Occupation in a baking-related job was identi fied from the subjects' job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status. Results: 19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95{\%} CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared. Discussion: The findings from this study do not suggest increased lung cancer risks in baking-related professions.",
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T1 - Lung cancer risk among bakers, pastrycooks and confectionary makers

T2 - The SYNERGY study

AU - Behrens, Thomas

AU - Kendzia, Benjamin

AU - Treppmann, Tabea

AU - Olsson, Ann

AU - Jöckel, Karl Heinz

AU - Gustavsson, Per

AU - Pohlabeln, Hermann

AU - Ahrens, Wolfgang

AU - Brüske, Irene

AU - Wichmann, Hans Erich

AU - Merletti, Franco

AU - Mirabelli, Dario

AU - Richiardi, Lorenzo

AU - Simonato, Lorenzo

AU - Zaridze, David

AU - Szeszenia-Dabrowska, Neonila

AU - Rudnai, P.

AU - Lissowska, Jolanta

AU - Fabianova, Eleonora

AU - Tardón, Adonina

AU - Field, John

AU - Dumitru, Rodica Stanescu

AU - Bencko, Vladimir

AU - Foretova, Lenka

AU - Janout, Vladimir

AU - Siemiatycki, Jack

AU - Parent, Marie Elise

AU - McLaughlin, John

AU - Demers, Paul

AU - Landi, Maria Teresa

AU - Caporaso, Neil

AU - Kromhout, Hans

AU - Vermeulen, Roel

AU - Peters, Susan

AU - Benhamou, Simone

AU - Stücker, Isabelle

AU - Guida, Florence

AU - Consonni, Dario

AU - Bueno-de-Mesquita, Bas

AU - Mannetje, Andrea T.

AU - Pearce, Neil

AU - Tse, Lap Ah

AU - Yu, Ignatius Tak Sun

AU - Plato, Nils

AU - Boffetta, Paolo

AU - Straif, Kurt

AU - Schüz, Joachim

AU - Pesch, Beate

AU - Brüning, Thomas

PY - 2013/11

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AB - Introduction: Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries. Methods: Occupation in a baking-related job was identi fied from the subjects' job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status. Results: 19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95% CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared. Discussion: The findings from this study do not suggest increased lung cancer risks in baking-related professions.

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