Lower prevalence of chromosome aberrations and SCEs in self-poisoned pregnant women

T. T.T. Huong, I. Szentesi, A. Czeizel

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A cytogenetic investigation was conducted in 18 self-poisoned pregnant and 16 self-poisoned non-pregnant women and in 31 pregnant and non-pregnant controls. Blood samples for analysis of chromosomal aberrations and SCEs were collected from women who were at different early stages of pregnancy. The difference between self-poisoned women and controls was very highly significant in the case of chromatid-type and unstable chromosome-type aberrations and highly significant in the case of SCEs. Further, the frequency of chromatid aberrations in pregnant women relative to non-pregnant ones was significantly lower suggesting a possible protective effect of pregnancy.

Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
Volume198
Issue number1
DOIs
Publication statusPublished - Mar 1988

Keywords

  • Chromosome aberrations
  • Pregnant women
  • SCE
  • Suicide
  • self-poisoned

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Health, Toxicology and Mutagenesis

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