Loss of monocyte membrane receptors in patients with SLE

M. Kavai, K. Lukacs, I. Sonkoly, I. J. Jókay, A. Berndt, G. Szegedi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Following an 80-min cold treatment of monocytes and their subsequent heating at 37°C a part of the Fc and C3 receptors is shed from the cells into the serum-free medium. However, while the reduced expression of cell membrane Fc receptors is regenerated at 37°C in 4-8 hr, that of the C3 receptors is not. Initially, the Fc receptor expression of monocytes for patients with SLE is greater than that of controls and after shedding it increases to the level of controls at 37°C in 4-8 hr. The expression and the regeneration of C3 receptors are equivalent to those of controls. The phagocytic ability of patient monocytes is lower than that of controls and the difference also remains after heat treatment.

Original languageEnglish
Pages (from-to)66-71
Number of pages6
JournalClinical and Experimental Immunology
Volume40
Issue number1
Publication statusPublished - 1980

Fingerprint

Fc Receptors
Monocytes
Membranes
Serum-Free Culture Media
Heating
Regeneration
Hot Temperature
Cell Membrane
Therapeutics

ASJC Scopus subject areas

  • Immunology

Cite this

Kavai, M., Lukacs, K., Sonkoly, I., Jókay, I. J., Berndt, A., & Szegedi, G. (1980). Loss of monocyte membrane receptors in patients with SLE. Clinical and Experimental Immunology, 40(1), 66-71.

Loss of monocyte membrane receptors in patients with SLE. / Kavai, M.; Lukacs, K.; Sonkoly, I.; Jókay, I. J.; Berndt, A.; Szegedi, G.

In: Clinical and Experimental Immunology, Vol. 40, No. 1, 1980, p. 66-71.

Research output: Contribution to journalArticle

Kavai, M, Lukacs, K, Sonkoly, I, Jókay, IJ, Berndt, A & Szegedi, G 1980, 'Loss of monocyte membrane receptors in patients with SLE', Clinical and Experimental Immunology, vol. 40, no. 1, pp. 66-71.
Kavai M, Lukacs K, Sonkoly I, Jókay IJ, Berndt A, Szegedi G. Loss of monocyte membrane receptors in patients with SLE. Clinical and Experimental Immunology. 1980;40(1):66-71.
Kavai, M. ; Lukacs, K. ; Sonkoly, I. ; Jókay, I. J. ; Berndt, A. ; Szegedi, G. / Loss of monocyte membrane receptors in patients with SLE. In: Clinical and Experimental Immunology. 1980 ; Vol. 40, No. 1. pp. 66-71.
@article{9b0b68ee6a97423ea501c51e41a7552f,
title = "Loss of monocyte membrane receptors in patients with SLE",
abstract = "Following an 80-min cold treatment of monocytes and their subsequent heating at 37°C a part of the Fc and C3 receptors is shed from the cells into the serum-free medium. However, while the reduced expression of cell membrane Fc receptors is regenerated at 37°C in 4-8 hr, that of the C3 receptors is not. Initially, the Fc receptor expression of monocytes for patients with SLE is greater than that of controls and after shedding it increases to the level of controls at 37°C in 4-8 hr. The expression and the regeneration of C3 receptors are equivalent to those of controls. The phagocytic ability of patient monocytes is lower than that of controls and the difference also remains after heat treatment.",
author = "M. Kavai and K. Lukacs and I. Sonkoly and J{\'o}kay, {I. J.} and A. Berndt and G. Szegedi",
year = "1980",
language = "English",
volume = "40",
pages = "66--71",
journal = "Clinical and Experimental Immunology",
issn = "0009-9104",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Loss of monocyte membrane receptors in patients with SLE

AU - Kavai, M.

AU - Lukacs, K.

AU - Sonkoly, I.

AU - Jókay, I. J.

AU - Berndt, A.

AU - Szegedi, G.

PY - 1980

Y1 - 1980

N2 - Following an 80-min cold treatment of monocytes and their subsequent heating at 37°C a part of the Fc and C3 receptors is shed from the cells into the serum-free medium. However, while the reduced expression of cell membrane Fc receptors is regenerated at 37°C in 4-8 hr, that of the C3 receptors is not. Initially, the Fc receptor expression of monocytes for patients with SLE is greater than that of controls and after shedding it increases to the level of controls at 37°C in 4-8 hr. The expression and the regeneration of C3 receptors are equivalent to those of controls. The phagocytic ability of patient monocytes is lower than that of controls and the difference also remains after heat treatment.

AB - Following an 80-min cold treatment of monocytes and their subsequent heating at 37°C a part of the Fc and C3 receptors is shed from the cells into the serum-free medium. However, while the reduced expression of cell membrane Fc receptors is regenerated at 37°C in 4-8 hr, that of the C3 receptors is not. Initially, the Fc receptor expression of monocytes for patients with SLE is greater than that of controls and after shedding it increases to the level of controls at 37°C in 4-8 hr. The expression and the regeneration of C3 receptors are equivalent to those of controls. The phagocytic ability of patient monocytes is lower than that of controls and the difference also remains after heat treatment.

UR - http://www.scopus.com/inward/record.url?scp=0018858291&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018858291&partnerID=8YFLogxK

M3 - Article

C2 - 7389218

AN - SCOPUS:0018858291

VL - 40

SP - 66

EP - 71

JO - Clinical and Experimental Immunology

JF - Clinical and Experimental Immunology

SN - 0009-9104

IS - 1

ER -