Longevity treatment with (-)deprenyl in female RATS: Effect on copulatory activity and lifespan

J. Dalló, L. Köles

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Six months old ovariectomized female rats (n=9) were treated with (-)deprenyl in a dose of 0.25 mg/kg s.c. three times a week, and (n=9) with physiologic saline (0.1 ml/100 g) till decay. It was found that control females (n=9) decayed within the age of fifteen months while the members of the (-)deprenyl treated group were all alive at that age. Moreover three (-)deprenyl treated female rats reached 36 months of age. Sexual activity was quite absent in both groups. The data suggests that (-)deprenyl extended the lifespan of female rats only in total absence of gonadal hormones and sexual activity.

Original languageEnglish
Pages (from-to)277-278
Number of pages2
JournalActa physiologica Hungarica
Volume84
Issue number3
Publication statusPublished - Dec 1 1996

Keywords

  • (-)Deprenyl
  • Copulatory activity
  • Female rat
  • Lifespan

ASJC Scopus subject areas

  • Physiology (medical)

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