Liquid chromatography-mass spectrometry coupling and its application in pharmaceutical research

K. Vekey, D. Edwards, L. F. Zerilli

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The advantages and technical problems related to the on-line connection of liquid chromatography and mass spectrometry are described, with special emphasis on applications in pharmaceutical chemistry. The most important characteristics of various interfaces, such as direct liquid introduction, Magic, continous flow fast atom bombardment and thermospray, are discussed. Special applications to the study of thermally very labile compounds are considered.

Original languageEnglish
Pages (from-to)73-85
Number of pages13
JournalJournal of Chromatography B: Biomedical Sciences and Applications
Volume488
Issue number1
DOIs
Publication statusPublished - Mar 17 1989

ASJC Scopus subject areas

  • Chemistry(all)

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