The advantages and technical problems related to the on-line connection of liquid chromatography and mass spectrometry are described, with special emphasis on applications in pharmaceutical chemistry. The most important characteristics of various interfaces, such as direct liquid introduction, Magic, continous flow fast atom bombardment and thermospray, are discussed. Special applications to the study of thermally very labile compounds are considered.
|Number of pages||13|
|Journal||Journal of Chromatography B: Biomedical Sciences and Applications|
|Publication status||Published - Mar 17 1989|
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