The percutaneous absorption of liposomes (prepared from NAT 106) was investigated with radioactively labelled substances in comparison with percutaneous absorption without liposomes (controls) in vivo on the skin of young pigs. Radioactivity was monitored as a function of time in skin tissue, plasma or blood and in urine. Elevated tissue levels, increased absorption and renal elimination of the various liposomal preparations in comparison to the controls were measured.
|Number of pages||4|
|Publication status||Published - Dec 1 1990|
- drug carriers, percutaneous
- liposomes, absorption, penetration
- sodium pertechnate
ASJC Scopus subject areas
- Drug Discovery