Liposomes from soya phospholipids as percutaneous drug carriers. 1st Communication

Qualitative in vivo investigations with antibody-loaded liposomes

C. Artmann, J. Roding, M. Ghyczy-, H. G. Pratzel

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The penetration behaviour of liposome (prepared from NAT 106)-incorporated proteins was investigated in vivo by use of monoclonal antibodies (MOAB) as model substances on the skin of young pigs. Within 20 min of topical application, an even distribution of liposome-incorporated antibodies through all skin layers could be shown by means of an immunohistochemical stain.

Original languageEnglish
Pages (from-to)1363-1365
Number of pages3
JournalArzneimittel-Forschung
Volume40
Issue number12
Publication statusPublished - 1990

Fingerprint

Drug Carriers
Liposomes
Phospholipids
Skin
Communication
Antibodies
Coloring Agents
Swine
Monoclonal Antibodies
Proteins
N-acetyltalosaminuronic acid

Keywords

  • drug carriers, percutaneous
  • liposomes, penetration
  • proteins, liposome-incorporated, penetration

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

Liposomes from soya phospholipids as percutaneous drug carriers. 1st Communication : Qualitative in vivo investigations with antibody-loaded liposomes. / Artmann, C.; Roding, J.; Ghyczy-, M.; Pratzel, H. G.

In: Arzneimittel-Forschung, Vol. 40, No. 12, 1990, p. 1363-1365.

Research output: Contribution to journalArticle

@article{0553531c6eec42158cb153724a575ea8,
title = "Liposomes from soya phospholipids as percutaneous drug carriers. 1st Communication: Qualitative in vivo investigations with antibody-loaded liposomes",
abstract = "The penetration behaviour of liposome (prepared from NAT 106)-incorporated proteins was investigated in vivo by use of monoclonal antibodies (MOAB) as model substances on the skin of young pigs. Within 20 min of topical application, an even distribution of liposome-incorporated antibodies through all skin layers could be shown by means of an immunohistochemical stain.",
keywords = "drug carriers, percutaneous, liposomes, penetration, proteins, liposome-incorporated, penetration",
author = "C. Artmann and J. Roding and M. Ghyczy- and Pratzel, {H. G.}",
year = "1990",
language = "English",
volume = "40",
pages = "1363--1365",
journal = "Drug Research",
issn = "2194-9379",
publisher = "Thieme",
number = "12",

}

TY - JOUR

T1 - Liposomes from soya phospholipids as percutaneous drug carriers. 1st Communication

T2 - Qualitative in vivo investigations with antibody-loaded liposomes

AU - Artmann, C.

AU - Roding, J.

AU - Ghyczy-, M.

AU - Pratzel, H. G.

PY - 1990

Y1 - 1990

N2 - The penetration behaviour of liposome (prepared from NAT 106)-incorporated proteins was investigated in vivo by use of monoclonal antibodies (MOAB) as model substances on the skin of young pigs. Within 20 min of topical application, an even distribution of liposome-incorporated antibodies through all skin layers could be shown by means of an immunohistochemical stain.

AB - The penetration behaviour of liposome (prepared from NAT 106)-incorporated proteins was investigated in vivo by use of monoclonal antibodies (MOAB) as model substances on the skin of young pigs. Within 20 min of topical application, an even distribution of liposome-incorporated antibodies through all skin layers could be shown by means of an immunohistochemical stain.

KW - drug carriers, percutaneous

KW - liposomes, penetration

KW - proteins, liposome-incorporated, penetration

UR - http://www.scopus.com/inward/record.url?scp=0025598348&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025598348&partnerID=8YFLogxK

M3 - Article

VL - 40

SP - 1363

EP - 1365

JO - Drug Research

JF - Drug Research

SN - 2194-9379

IS - 12

ER -