Lipid-Peroxidation in vivo--Lipid-Membran-Interaktion hervorgerufen durch experimentelle Hyperoxie, Hypoxie und Ischämie im Herzmuskel.

Translated title of the contribution: Lipid peroxidation in vivo--lipid-membrane interaction induced by hyperoxia, hypoxia and ischemia in the heart muscle

B. Török, E. Röth, B. Matkovics

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Rat and dog experiments were undertaken to describe the range of the endogenous lipid peroxidation (measured by formation of malondialdehyde in heart tissue) and to analyze the effects of hyperoxic, hypoxic and ischemic influences. The acute hyperoxia caused a moderate increase in the lipid peroxidation. The malondialdehyde formation was perceptibly higher in hypoxia, while the highest values were found in ischemic hearts. It can be concluded that the cytotoxic oxygen metabolites cause unfavourable influences on the heart structure and function, for this reason an antioxidant therapy is to be recommended.

Translated title of the contributionLipid peroxidation in vivo--lipid-membrane interaction induced by hyperoxia, hypoxia and ischemia in the heart muscle
Original languageGerman
Pages (from-to)142-151
Number of pages10
JournalZeitschrift fur Experimentelle Chirurgie Transplantation und Kunstliche Organe
Volume17
Issue number3
Publication statusPublished - Jan 1 1984

ASJC Scopus subject areas

  • Transplantation

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