Limitation of the long-lived 121Te contaminant in production of 123I through the 124Xe(p,x) route

A. Hermanne, F. Tarkanyi, S. Takacs, R. Adam Rebeles, A. Ignatyuk, S. Spellerberg, R. Schweikert

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The 13.2h half-life radioisotope 123I is widely used in clinical nuclear medicine diagnosis. At present it is mostly produced in nca form by proton irradiation of highly enriched 124Xe in dedicated gas target set-ups and relying on the decay chain 123Cs-123Xe-123I.Depending on the irradiation conditions contamination with long-lived 121Te, a daughter product of the co-produced rather short lived 121I, occurs and can limit the useful shelf life of the 123I solution. Excitation function of the 124Xe(p,α)121I, 124Xe(p,2n)123Cs and 124Xe(p,2p)123Xe reactions are measured up to 35MeV using the stacked gas cell technique and high-resolution γ-ray spectrometry. The experimental data were compared with the earlier literature values, with new results of the ALICE-IPPE and EMPIRE-II codes and with the data taken from the TENDL-2009 database. Existing discrepancies in cross-section data are largely solved and new recommended values are proposed. From fits to the new excitation curves integral 123I batch yields and 121Te contaminations for realistic production conditions are derived. Optimization of irradiation and cooling times and energy degradation in the target can strongly influence the contamination level.

Original languageEnglish
Pages (from-to)358-368
Number of pages11
JournalApplied Radiation and Isotopes
Volume69
Issue number2
DOIs
Publication statusPublished - Feb 1 2011

Keywords

  • Cross sections
  • I -Te contamination
  • I production
  • Nuclear model calculations
  • Xe and I isotopes
  • Xe gas cells

ASJC Scopus subject areas

  • Radiation

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