Light- and electron-microscopic visualization of γ-aminobutyric acid and GABA-transaminase in the oviduct of rats - Predominant occurrence in epithelium

S. L. Erdö, J. Somogyi, J. Hámori, F. Amenta

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The distribution in the rat oviduct of γ-aminobutyric acid and its catabolic enzyme GABA-transaminase was studied by the use of immunocytochemical and enzymehistochemical techniques. At the light-microscopic level, both GABA immunoreactivity and GABA-transaminase enzyme reactivity were found primarily in the tubal epithelium while in the muscle layers of the organ only a faint GABA and GABA-transaminase positive staining could be detected. Electron-microscopic evaluation of the GABA immunoreactivity revealed a heavy labelling of the basal bodies (kinetosomes) and a moderate staining of the cilia. These findings indicate that the role of GABA in the oviduct is not related to neurotransmission but may be related to ciliary functions.

Original languageEnglish
Pages (from-to)621-626
Number of pages6
JournalCell and Tissue Research
Volume244
Issue number3
DOIs
Publication statusPublished - Jun 1986

Fingerprint

4-Aminobutyrate Transaminase
Aminobutyrates
Oviducts
gamma-Aminobutyric Acid
Rats
Visualization
Epithelium
Electrons
Basal Bodies
Light
Staining and Labeling
Cilia
Enzymes
Synaptic Transmission
Labeling
Muscle
Muscles

Keywords

  • Basal bodies
  • Cilia
  • GABA
  • GABA-transaminase
  • Oviduct
  • Rat

ASJC Scopus subject areas

  • Anatomy
  • Clinical Biochemistry
  • Cell Biology

Cite this

Light- and electron-microscopic visualization of γ-aminobutyric acid and GABA-transaminase in the oviduct of rats - Predominant occurrence in epithelium. / Erdö, S. L.; Somogyi, J.; Hámori, J.; Amenta, F.

In: Cell and Tissue Research, Vol. 244, No. 3, 06.1986, p. 621-626.

Research output: Contribution to journalArticle

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