Light- and electron-microscopic visualization of γ-aminobutyric acid and GABA-transaminase in the oviduct of rats - Predominant occurrence in epithelium

S. L. Erdö, J. Somogyi, J. Hámori, F. Amenta

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16 Citations (Scopus)

Abstract

The distribution in the rat oviduct of γ-aminobutyric acid and its catabolic enzyme GABA-transaminase was studied by the use of immunocytochemical and enzymehistochemical techniques. At the light-microscopic level, both GABA immunoreactivity and GABA-transaminase enzyme reactivity were found primarily in the tubal epithelium while in the muscle layers of the organ only a faint GABA and GABA-transaminase positive staining could be detected. Electron-microscopic evaluation of the GABA immunoreactivity revealed a heavy labelling of the basal bodies (kinetosomes) and a moderate staining of the cilia. These findings indicate that the role of GABA in the oviduct is not related to neurotransmission but may be related to ciliary functions.

Original languageEnglish
Pages (from-to)621-626
Number of pages6
JournalCell And Tissue Research
Volume244
Issue number3
DOIs
Publication statusPublished - Jun 1 1986

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Keywords

  • Basal bodies
  • Cilia
  • GABA
  • GABA-transaminase
  • Oviduct
  • Rat

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology

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