Light- and electron microscopic investigations on the median eminence of the pigeon after TSH and PTU treatment

K. Elekes, Péter Péczely

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1 Citation (Scopus)

Abstract

1. The effects of TSH and PTU treatment with thyroid stimulating hormone and propylthiouracil on the structure of median eminence of the pigeon have been studied by light- and electron microscopy. 2. By light microscopy it has been found that the aldehydefuchsin positive material of the external layers of the anterior median eminence differs functionally from that of the neural lobe. 3. The light- and electron microscopic investigations revealed that the anterior and posterior median eminence differ both structurally and functionally. Specifically after the experimental interventions the considerable reaction can be observed only in the anterior median eminence. 4. Electron microscopically it appears possible that the aldehyde-fuchsin positive material of the anterior median eminence may be associated with the 1200-1500 Å-size granules. 5. The quantitative changes observed in the granular composition after the treatments show a close correlation with thyroid function, namely after treatment with thyroid stimulating hormone the relative quantity of the 1200-1500 Å-size granules increases markedly, while administration of propylthiouracil has the opposite effect and increases the relative quantity of the 1000 Å-size dense-core vesicles. They presumably may play a role in the control of TSH-secretion.

Original languageEnglish
Pages (from-to)337-349
Number of pages13
JournalZeitschrift für Zellforschung und Mikroskopische Anatomie
Volume134
Issue number3
DOIs
Publication statusPublished - Sep 1972

Fingerprint

Propylthiouracil
Median Eminence
Columbidae
Thyrotropin
Optical microscopy
Electrons
Rosaniline Dyes
Light
Aldehydes
Electron microscopy
Posterior Pituitary Gland
Chemical analysis
Secretory Vesicles
Microscopy
Electron Microscopy
Thyroid Gland

Keywords

  • Light-and electron microscopy
  • Median eminence of birds
  • Neurosecretion
  • Thyrotrop function

ASJC Scopus subject areas

  • Anatomy
  • Clinical Biochemistry
  • Cell Biology
  • Medicine(all)

Cite this

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title = "Light- and electron microscopic investigations on the median eminence of the pigeon after TSH and PTU treatment",
abstract = "1. The effects of TSH and PTU treatment with thyroid stimulating hormone and propylthiouracil on the structure of median eminence of the pigeon have been studied by light- and electron microscopy. 2. By light microscopy it has been found that the aldehydefuchsin positive material of the external layers of the anterior median eminence differs functionally from that of the neural lobe. 3. The light- and electron microscopic investigations revealed that the anterior and posterior median eminence differ both structurally and functionally. Specifically after the experimental interventions the considerable reaction can be observed only in the anterior median eminence. 4. Electron microscopically it appears possible that the aldehyde-fuchsin positive material of the anterior median eminence may be associated with the 1200-1500 {\AA}-size granules. 5. The quantitative changes observed in the granular composition after the treatments show a close correlation with thyroid function, namely after treatment with thyroid stimulating hormone the relative quantity of the 1200-1500 {\AA}-size granules increases markedly, while administration of propylthiouracil has the opposite effect and increases the relative quantity of the 1000 {\AA}-size dense-core vesicles. They presumably may play a role in the control of TSH-secretion.",
keywords = "Light-and electron microscopy, Median eminence of birds, Neurosecretion, Thyrotrop function",
author = "K. Elekes and P{\'e}ter P{\'e}czely",
year = "1972",
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AU - Elekes, K.

AU - Péczely, Péter

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N2 - 1. The effects of TSH and PTU treatment with thyroid stimulating hormone and propylthiouracil on the structure of median eminence of the pigeon have been studied by light- and electron microscopy. 2. By light microscopy it has been found that the aldehydefuchsin positive material of the external layers of the anterior median eminence differs functionally from that of the neural lobe. 3. The light- and electron microscopic investigations revealed that the anterior and posterior median eminence differ both structurally and functionally. Specifically after the experimental interventions the considerable reaction can be observed only in the anterior median eminence. 4. Electron microscopically it appears possible that the aldehyde-fuchsin positive material of the anterior median eminence may be associated with the 1200-1500 Å-size granules. 5. The quantitative changes observed in the granular composition after the treatments show a close correlation with thyroid function, namely after treatment with thyroid stimulating hormone the relative quantity of the 1200-1500 Å-size granules increases markedly, while administration of propylthiouracil has the opposite effect and increases the relative quantity of the 1000 Å-size dense-core vesicles. They presumably may play a role in the control of TSH-secretion.

AB - 1. The effects of TSH and PTU treatment with thyroid stimulating hormone and propylthiouracil on the structure of median eminence of the pigeon have been studied by light- and electron microscopy. 2. By light microscopy it has been found that the aldehydefuchsin positive material of the external layers of the anterior median eminence differs functionally from that of the neural lobe. 3. The light- and electron microscopic investigations revealed that the anterior and posterior median eminence differ both structurally and functionally. Specifically after the experimental interventions the considerable reaction can be observed only in the anterior median eminence. 4. Electron microscopically it appears possible that the aldehyde-fuchsin positive material of the anterior median eminence may be associated with the 1200-1500 Å-size granules. 5. The quantitative changes observed in the granular composition after the treatments show a close correlation with thyroid function, namely after treatment with thyroid stimulating hormone the relative quantity of the 1200-1500 Å-size granules increases markedly, while administration of propylthiouracil has the opposite effect and increases the relative quantity of the 1000 Å-size dense-core vesicles. They presumably may play a role in the control of TSH-secretion.

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KW - Neurosecretion

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