Light and electron microscopic immunocytochemical localization of adrenocorticotrophin-like activity in rat cerebellar and red nuclei

C. Léránth, T. H. Williams, J. Hámori, M. Chrétien

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Abstract

An antiserum raised to synthetic adrenocorticotrophin (ACTH) was bound to large neurons of the cerebellar nuclei in rat. In these neurons, the matrix microtubules of the cell bodies and dendritic processes were ACTH-positive. In the axon terminals, 40 nm diameter clear synaptic vesicles were stained in both the deep cerebellar nuclei and red nucleus. Following transection of the superior cerebellar peduncle, ACTH-labeled terminals disappeared in the red nucleus, suggesting that the ACTH-labeled neurons were projection neurons of the cerebellar nuclei.

Original languageEnglish
Pages (from-to)481-487
Number of pages7
JournalNeuroscience
Volume6
Issue number3
DOIs
Publication statusPublished - 1981

Fingerprint

Red Nucleus
Cerebellar Nuclei
Adrenocorticotropic Hormone
Electrons
Neurons
Light
Synaptic Vesicles
Presynaptic Terminals
Microtubules
Immune Sera

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Light and electron microscopic immunocytochemical localization of adrenocorticotrophin-like activity in rat cerebellar and red nuclei. / Léránth, C.; Williams, T. H.; Hámori, J.; Chrétien, M.

In: Neuroscience, Vol. 6, No. 3, 1981, p. 481-487.

Research output: Contribution to journalArticle

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