Life expectancy in chronic liver disease.

L. Szalay, C. Göndöcs, M. Kárteszi, Z. Schaff, K. Lapis, J. Fehér

Research output: Contribution to journalArticle

Abstract

Life-table analysis is a suitable method for evaluating the effectiveness of therapeutical approaches to and the progression of, chronic diseases. The authors performed 324 liver biopsies in patients with liver disease between 1976 and 1986. The cumulative life-table analysis of Cutler and Ederer was applied in this retrospective study. Survival rates of different groups of patients expressed as the 7-year life expectancy were as follows: toxic hepatitis 90%, steatosis hepatitis 87%, chronic persistent hepatitis 87%, nonspecific reactive hepatitis 76%, chronic active hepatitis 72%, acute alcoholic hepatitis 66%, liver cirrhosis 40%. There seems to be a correlation between the severity of histological alteration and live expectancy. A similar correlation between the inflammatory cell infiltration and life expectancy cannot be observed. The life expectancy of patients with chronic active hepatitis has significantly improved recently. Further improvement of survival of patients with liver cirrhosis can be expected only from a reduction of alcohol consumption. The results can be regarded as a reference data for life expectancy of patients with chronic liver disease in Hungary.

Original languageEnglish
Pages (from-to)297-305
Number of pages9
JournalActa Medica Hungarica
Volume45
Issue number3-4
Publication statusPublished - 1988

Fingerprint

Life Expectancy
Liver Diseases
Chronic Disease
Chronic Hepatitis
Life Tables
Liver Cirrhosis
Hepatitis
Alcoholic Hepatitis
Chemical and Drug Induced Liver Injury
Hungary
Alcohol Drinking
Survival Rate
Retrospective Studies
Biopsy
Survival
Liver

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Szalay, L., Göndöcs, C., Kárteszi, M., Schaff, Z., Lapis, K., & Fehér, J. (1988). Life expectancy in chronic liver disease. Acta Medica Hungarica, 45(3-4), 297-305.

Life expectancy in chronic liver disease. / Szalay, L.; Göndöcs, C.; Kárteszi, M.; Schaff, Z.; Lapis, K.; Fehér, J.

In: Acta Medica Hungarica, Vol. 45, No. 3-4, 1988, p. 297-305.

Research output: Contribution to journalArticle

Szalay, L, Göndöcs, C, Kárteszi, M, Schaff, Z, Lapis, K & Fehér, J 1988, 'Life expectancy in chronic liver disease.', Acta Medica Hungarica, vol. 45, no. 3-4, pp. 297-305.
Szalay, L. ; Göndöcs, C. ; Kárteszi, M. ; Schaff, Z. ; Lapis, K. ; Fehér, J. / Life expectancy in chronic liver disease. In: Acta Medica Hungarica. 1988 ; Vol. 45, No. 3-4. pp. 297-305.
@article{95184e4602b4425086a78225107e67ca,
title = "Life expectancy in chronic liver disease.",
abstract = "Life-table analysis is a suitable method for evaluating the effectiveness of therapeutical approaches to and the progression of, chronic diseases. The authors performed 324 liver biopsies in patients with liver disease between 1976 and 1986. The cumulative life-table analysis of Cutler and Ederer was applied in this retrospective study. Survival rates of different groups of patients expressed as the 7-year life expectancy were as follows: toxic hepatitis 90{\%}, steatosis hepatitis 87{\%}, chronic persistent hepatitis 87{\%}, nonspecific reactive hepatitis 76{\%}, chronic active hepatitis 72{\%}, acute alcoholic hepatitis 66{\%}, liver cirrhosis 40{\%}. There seems to be a correlation between the severity of histological alteration and live expectancy. A similar correlation between the inflammatory cell infiltration and life expectancy cannot be observed. The life expectancy of patients with chronic active hepatitis has significantly improved recently. Further improvement of survival of patients with liver cirrhosis can be expected only from a reduction of alcohol consumption. The results can be regarded as a reference data for life expectancy of patients with chronic liver disease in Hungary.",
author = "L. Szalay and C. G{\"o}nd{\"o}cs and M. K{\'a}rteszi and Z. Schaff and K. Lapis and J. Feh{\'e}r",
year = "1988",
language = "English",
volume = "45",
pages = "297--305",
journal = "Acta Medica Hungarica",
issn = "0236-5286",
publisher = "Akademiai Kiado",
number = "3-4",

}

TY - JOUR

T1 - Life expectancy in chronic liver disease.

AU - Szalay, L.

AU - Göndöcs, C.

AU - Kárteszi, M.

AU - Schaff, Z.

AU - Lapis, K.

AU - Fehér, J.

PY - 1988

Y1 - 1988

N2 - Life-table analysis is a suitable method for evaluating the effectiveness of therapeutical approaches to and the progression of, chronic diseases. The authors performed 324 liver biopsies in patients with liver disease between 1976 and 1986. The cumulative life-table analysis of Cutler and Ederer was applied in this retrospective study. Survival rates of different groups of patients expressed as the 7-year life expectancy were as follows: toxic hepatitis 90%, steatosis hepatitis 87%, chronic persistent hepatitis 87%, nonspecific reactive hepatitis 76%, chronic active hepatitis 72%, acute alcoholic hepatitis 66%, liver cirrhosis 40%. There seems to be a correlation between the severity of histological alteration and live expectancy. A similar correlation between the inflammatory cell infiltration and life expectancy cannot be observed. The life expectancy of patients with chronic active hepatitis has significantly improved recently. Further improvement of survival of patients with liver cirrhosis can be expected only from a reduction of alcohol consumption. The results can be regarded as a reference data for life expectancy of patients with chronic liver disease in Hungary.

AB - Life-table analysis is a suitable method for evaluating the effectiveness of therapeutical approaches to and the progression of, chronic diseases. The authors performed 324 liver biopsies in patients with liver disease between 1976 and 1986. The cumulative life-table analysis of Cutler and Ederer was applied in this retrospective study. Survival rates of different groups of patients expressed as the 7-year life expectancy were as follows: toxic hepatitis 90%, steatosis hepatitis 87%, chronic persistent hepatitis 87%, nonspecific reactive hepatitis 76%, chronic active hepatitis 72%, acute alcoholic hepatitis 66%, liver cirrhosis 40%. There seems to be a correlation between the severity of histological alteration and live expectancy. A similar correlation between the inflammatory cell infiltration and life expectancy cannot be observed. The life expectancy of patients with chronic active hepatitis has significantly improved recently. Further improvement of survival of patients with liver cirrhosis can be expected only from a reduction of alcohol consumption. The results can be regarded as a reference data for life expectancy of patients with chronic liver disease in Hungary.

UR - http://www.scopus.com/inward/record.url?scp=0024262509&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024262509&partnerID=8YFLogxK

M3 - Article

VL - 45

SP - 297

EP - 305

JO - Acta Medica Hungarica

JF - Acta Medica Hungarica

SN - 0236-5286

IS - 3-4

ER -