Leukocyte migration inhibition by a specific antigen in human brucellosis

G. Nyerges, L. Telegdy

Research output: Contribution to journalArticle

Abstract

Leukocyte migration inhibition /LMI/ tests were carried out in 19 patients with Brucella abortus bovis infection and in 18 healthy control subjects using killed Brucella abortus bovis as antigen. In the brucellosis group a statistically significant LMI was observed, as compared to the members of the control group. Using the same antigen, a fairly good correlation was found between the local skin reaction and the results of the LMI test in the subacute or chronic stage of the disease. However, the results of the LMI test showed no correlation with either the clinical activity of the disease or the serological results and the general reactions elicited by the skin test. Since LMI and skin tests give nearly identical results in subacute or chronic brucellosis, it is suggested that the LMI test may be used as a safe test instead of the skin test.

Original languageEnglish
Pages (from-to)213-216
Number of pages4
JournalInfection
Volume3
Issue number4
DOIs
Publication statusPublished - Dec 1975

Fingerprint

Brucellosis
Skin Tests
Brucella abortus
Leukocytes
Antigens
Leukocyte Cell Migration Assays
Healthy Volunteers
Chronic Disease
Control Groups
Skin
Infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology

Cite this

Leukocyte migration inhibition by a specific antigen in human brucellosis. / Nyerges, G.; Telegdy, L.

In: Infection, Vol. 3, No. 4, 12.1975, p. 213-216.

Research output: Contribution to journalArticle

@article{ad86d3509f8c40ffbc17cfe92dc45851,
title = "Leukocyte migration inhibition by a specific antigen in human brucellosis",
abstract = "Leukocyte migration inhibition /LMI/ tests were carried out in 19 patients with Brucella abortus bovis infection and in 18 healthy control subjects using killed Brucella abortus bovis as antigen. In the brucellosis group a statistically significant LMI was observed, as compared to the members of the control group. Using the same antigen, a fairly good correlation was found between the local skin reaction and the results of the LMI test in the subacute or chronic stage of the disease. However, the results of the LMI test showed no correlation with either the clinical activity of the disease or the serological results and the general reactions elicited by the skin test. Since LMI and skin tests give nearly identical results in subacute or chronic brucellosis, it is suggested that the LMI test may be used as a safe test instead of the skin test.",
author = "G. Nyerges and L. Telegdy",
year = "1975",
month = "12",
doi = "10.1007/BF01642768",
language = "English",
volume = "3",
pages = "213--216",
journal = "Infection",
issn = "0300-8126",
publisher = "Urban und Vogel",
number = "4",

}

TY - JOUR

T1 - Leukocyte migration inhibition by a specific antigen in human brucellosis

AU - Nyerges, G.

AU - Telegdy, L.

PY - 1975/12

Y1 - 1975/12

N2 - Leukocyte migration inhibition /LMI/ tests were carried out in 19 patients with Brucella abortus bovis infection and in 18 healthy control subjects using killed Brucella abortus bovis as antigen. In the brucellosis group a statistically significant LMI was observed, as compared to the members of the control group. Using the same antigen, a fairly good correlation was found between the local skin reaction and the results of the LMI test in the subacute or chronic stage of the disease. However, the results of the LMI test showed no correlation with either the clinical activity of the disease or the serological results and the general reactions elicited by the skin test. Since LMI and skin tests give nearly identical results in subacute or chronic brucellosis, it is suggested that the LMI test may be used as a safe test instead of the skin test.

AB - Leukocyte migration inhibition /LMI/ tests were carried out in 19 patients with Brucella abortus bovis infection and in 18 healthy control subjects using killed Brucella abortus bovis as antigen. In the brucellosis group a statistically significant LMI was observed, as compared to the members of the control group. Using the same antigen, a fairly good correlation was found between the local skin reaction and the results of the LMI test in the subacute or chronic stage of the disease. However, the results of the LMI test showed no correlation with either the clinical activity of the disease or the serological results and the general reactions elicited by the skin test. Since LMI and skin tests give nearly identical results in subacute or chronic brucellosis, it is suggested that the LMI test may be used as a safe test instead of the skin test.

UR - http://www.scopus.com/inward/record.url?scp=0016701130&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016701130&partnerID=8YFLogxK

U2 - 10.1007/BF01642768

DO - 10.1007/BF01642768

M3 - Article

VL - 3

SP - 213

EP - 216

JO - Infection

JF - Infection

SN - 0300-8126

IS - 4

ER -