Mire tanítanak a vérnyomáscsökkentokkel végzett újabb renoprotektív vizsgálatok?

Translated title of the contribution: Lessons from the novel renoprotective studies made by antihypertensive drugs

László Bajnok, I. Belgyógyászati Klinika

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

From the evaluated ONTARGET, ALTITUDE, ACCOMPLISH, ROADMAP, and ACCORD-BP studies a conclusion can be drawn that though microalbuminuria/proteinuria is a strong epidemiological biomarker, in interventional studies it is not necessarily a reliable surrogate endpoint as actual renal function may change in an opposite way. Namely, some therapeutic measures improving microalbuminuria/proteinuria may actually worsen renal function. In case of procedures such as blood pressure lowering or measure of RAS blockade an optimum point on a J-curve may exist. Orv. Hetil., 2013, 154, 243-247.

Translated title of the contributionLessons from the novel renoprotective studies made by antihypertensive drugs
Original languageHungarian
Pages (from-to)243-247
Number of pages5
JournalOrvosi hetilap
Volume154
Issue number7
DOIs
Publication statusPublished - Feb 18 2013

ASJC Scopus subject areas

  • Medicine(all)

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