Five equine herpesviruses are known to be widespread in horse populations of the world. Equine herpesviruses (EqHV)-1, 3, and 4 are members of the Alphaherpesvirinae subfamily (Patel and Heldens, 2005), whereas equine herpesviruses 2 and 5 are gammaherpesviruses. Equine betaherpesvirus is not known at present. Economically and epidemiologically the most important, EqHV-1 causes abortions, EqHV-3 causes coital exanthema, and EqHV-4 provokes mild respiratory disorders. The two gammaherpesviruses have not been associated with any certain disease (connection between EqHV-2 and Rhodococcus equi pneumonia is supposed). Most research on these viruses concentrate on clarifying their pathogenic role and on developing preventive vaccines against these agents. The molecular basis of latency/reactivation is poorly documented for equine herpesviruses. The sites of viral latency are mostly disputed.
ASJC Scopus subject areas
- Immunology and Microbiology(all)