Late consequences of cryogenic brain lesion in rat; an electrophysiological study

TarmáS Husz, Ferenc Joó, Andrea Antal, József Toldi

Research output: Contribution to journalArticle

4 Citations (Scopus)


The left somatosensory cortex of PVG/C rats was subjected to a transcranial cold lesion, spontaneous and evoked cortical activity was studied 2-3 weeks after the lesion. The spontaneous activity underwent a depression at the focus of the lesion. Close to the epicentre of the lesion, the amplitude of the potentials evoked by electrical stimulation of the contralateral whisker pad was considerably smaller than in the controls and an almost complete reduction of the initial positive phase was found. Perifo-cally, 3—4 mm from the epicentre, evoked potentials with enhanced amplitudes were recorded in all experiments. It seems that considerable damage took place at the epicentre of the lesion, while perifocally an excitatory (and/or inhibitory?) mechanism was activated.

Original languageEnglish
Pages (from-to)51-54
Number of pages4
Issue number1
Publication statusPublished - Jan 1992


  • Cryogenic lesion
  • Electrical stimulation
  • Evoked potentials
  • Somatosensory cortex

ASJC Scopus subject areas

  • Neuroscience(all)

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