Laparoscopic azygoportal disconnection procedure with a bipolar feedback controlled sealing system in a porcine model

A. Shamiyeh, R. Hubmann, L. Benkö, P. Vattay, E. Rőth, L. Tulipan, W. U. Wayand, J. Danis

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background. To examine the feasibility of a new, minimally invasive procedure for the devascularization of the proximal stomach and distal esophagus to prevent recurrent variceal bleeding in portal hypertension in a new animal model. Material and methods. Portal hypertension was created by laparoscopic clip ligation of the portal vein on 20 pigs. After 2 weeks the azygoportal disconnection procedure was performed with the LigaSure-ATLAS instrument. Results. There were 16 pigs out of 20 that survived both operations. Two died during introduction of anesthesia, one because of a cardiac arrest (second operation). One pig died resulting from necrosis of the gastric and esophageal wall. Autopsy (2 weeks later) showed that there was a complete arterial devascularization. At autopsy, none of the remaining 16 pigs had esophageal varices or necrosis of the stomach or esophagus. Conclusion. Laparoscopic azygoportal disconnection is a less invasive method for the prevention of rebleeding and seems to be safely performed with the LigaSure-ATLAS instrument.

Original languageEnglish
Pages (from-to)8-12
Number of pages5
JournalJournal of Surgical Research
Volume130
Issue number1
DOIs
Publication statusPublished - Jan 2006

Fingerprint

Swine
Stomach
Portal Hypertension
Esophagus
Autopsy
Necrosis
Esophageal and Gastric Varices
Portal Vein
Heart Arrest
Surgical Instruments
Ligation
Anesthesia
Animal Models
Hemorrhage

Keywords

  • Laparoscopy
  • LigaSure
  • Portal hypertension
  • Sugiura procedural

ASJC Scopus subject areas

  • Surgery

Cite this

Laparoscopic azygoportal disconnection procedure with a bipolar feedback controlled sealing system in a porcine model. / Shamiyeh, A.; Hubmann, R.; Benkö, L.; Vattay, P.; Rőth, E.; Tulipan, L.; Wayand, W. U.; Danis, J.

In: Journal of Surgical Research, Vol. 130, No. 1, 01.2006, p. 8-12.

Research output: Contribution to journalArticle

Shamiyeh, A. ; Hubmann, R. ; Benkö, L. ; Vattay, P. ; Rőth, E. ; Tulipan, L. ; Wayand, W. U. ; Danis, J. / Laparoscopic azygoportal disconnection procedure with a bipolar feedback controlled sealing system in a porcine model. In: Journal of Surgical Research. 2006 ; Vol. 130, No. 1. pp. 8-12.
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