A lamotrigin szerepe a herediter koproporfíriához társuló pszichotikus depresszió kezelésében - esettenulmány és rövid irodalmi áttekintés

Translated title of the contribution: Lamotrigine in the treatment of psychotic depression associated with hereditary coproporphyria - Case report and a brief review of the literature

Rozália Takács, Zoltán Makkos, Ákos Kassai-Farkas, Ágnes Pusztai, Gabor S. Ungvari, Gábor Gazdag

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: We report a successful treatment with lamotrigine of a patient with hereditary coproporphyria presenting with affective and psychotic symptoms. Case report: M.F., a 38-year-old, single woman was admitted to an acute psychiatric ward because of suddenly emerging psychosis. Ms F's hereditary coproporphyria was diagnosed 9 years before the current admission. While on treatment with olanzapine (20mg/day) the psychotic symptoms have gradually disappeared. In view of her significant mood fluctuations predominantly with depressed phases, lamotrigine was started and titrated up to 125 mg/day. Ms F's mood gradually became euthymic, suicidal ideations and anxiety disappeared. At 5-month follow-up, while still on lamotrigine, her porphyria was asymptomatic. Conclusion: To the best of our knowledge, this is the first report about the safe administration of lamotrigine in hereditary coproporphyria. Lamotrigine did not trigger an acute porphyric attack as confirmed by clinical and laboratory findings.

Translated title of the contributionLamotrigine in the treatment of psychotic depression associated with hereditary coproporphyria - Case report and a brief review of the literature
Original languageHungarian
Pages (from-to)43-46
Number of pages4
JournalNeuropsychopharmacologia Hungarica
Volume16
Issue number1
Publication statusPublished - Mar 2014

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Lamotrigine in the treatment of psychotic depression associated with hereditary coproporphyria - Case report and a brief review of the literature'. Together they form a unique fingerprint.

  • Cite this