Lack of the suckling-induced prolactin release in homozygous Barattleboro rats: the vasopressin-neurophysin-glycopeptide precursor may play a role in prolactin release

György Nagy, Jimmy D. Neill, G. Makara, B. Halász

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Suckling stimulus did not induce significant release of prolactin (PRL) in lactating homozygous Brattleboro rats, whereas it did it in heterozygous animals. Daily treatment of homozygous rats with vasopressin partly restored the PRL response to suckling. Findings suggest that vasopressin-neurophysin-glycopeptide precursor missing in homozygous Brattleboro rats may play a role in suckling-induced PRL release.

Original languageEnglish
Pages (from-to)165-167
Number of pages3
JournalBrain Research
Volume504
Issue number1
DOIs
Publication statusPublished - Dec 11 1989

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Neurophysins
Glycopeptides
Vasopressins
Brattleboro Rats
Prolactin

Keywords

  • Brattleboro rat
  • Prolactin
  • Suckling-induced release
  • Vasopressin-neurophysin precursor

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

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abstract = "Suckling stimulus did not induce significant release of prolactin (PRL) in lactating homozygous Brattleboro rats, whereas it did it in heterozygous animals. Daily treatment of homozygous rats with vasopressin partly restored the PRL response to suckling. Findings suggest that vasopressin-neurophysin-glycopeptide precursor missing in homozygous Brattleboro rats may play a role in suckling-induced PRL release.",
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T2 - the vasopressin-neurophysin-glycopeptide precursor may play a role in prolactin release

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AU - Neill, Jimmy D.

AU - Makara, G.

AU - Halász, B.

PY - 1989/12/11

Y1 - 1989/12/11

N2 - Suckling stimulus did not induce significant release of prolactin (PRL) in lactating homozygous Brattleboro rats, whereas it did it in heterozygous animals. Daily treatment of homozygous rats with vasopressin partly restored the PRL response to suckling. Findings suggest that vasopressin-neurophysin-glycopeptide precursor missing in homozygous Brattleboro rats may play a role in suckling-induced PRL release.

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KW - Vasopressin-neurophysin precursor

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