L-α-glycerylphosphorylcholine enhances the amplitude of the pattern electroretinogram in rhesus monkeys. A pilot study

A. Antal, S. Kéri, I. Bodis-Wollner

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The effects of L-α-glyceryl-phosphorylcholine (LGPC), a putative acetylcholine precursor, were studied on the pattern electroretinogram (PERG) in two rhesus monkeys. In the time interval 10-30 min after LGPC administration (85 mg/kg im.), the amplitude of the PERG increased significantly. In both monkeys the amplitude enhancement was more pronounced for low spatial frequency stimuli (1 cycle/degree) than for medium spatial frequency gratings (5 cycles/degree). This result suggests that besides the general facilitatory properties, LGPC may have specific spatial frequency tuning effects at the level of retinal information processing.

Original languageEnglish
Pages (from-to)407-412
Number of pages6
JournalNeurobiology
Volume7
Issue number4
Publication statusPublished - 1999

Fingerprint

Glycerylphosphorylcholine
Phosphorylcholine
Macaca mulatta
Automatic Data Processing
Acetylcholine
Haplorhini

Keywords

  • L-α-glycerylphosphorylcholine (LGPC)
  • Monkey
  • Pattern electroretinogram (PERG)
  • Spatial frequency

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

L-α-glycerylphosphorylcholine enhances the amplitude of the pattern electroretinogram in rhesus monkeys. A pilot study. / Antal, A.; Kéri, S.; Bodis-Wollner, I.

In: Neurobiology, Vol. 7, No. 4, 1999, p. 407-412.

Research output: Contribution to journalArticle

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