Kinetics of peroxynitrite formation and decay in diabetic rataorta

A. Nemeth, K. Stadler, J. Jakus, T. Vidoczy

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Detailed reaction mechanism compiled from literature was tested on diabetic rat aorta samples for which nitric oxide, superoxide formations and spin clearance rate were measured by electron paramagnetic resonance (EPR) method. The rate of superoxide formation was 1.0×10-7 M s-1. Kinetic calculations predicted ranges of nitric oxide formation rate and of nitric oxide, superoxide, peroxynitrite concentrations viable in the investigated biological entity.

Original languageEnglish
Pages (from-to)128-135
Number of pages8
JournalOxidation Communications
Volume34
Issue number1
Publication statusPublished - May 2 2011

Keywords

  • Nitric oxide
  • Reaction mechanism
  • Superoxide
  • Superoxide dismutase (SOD)
  • Tyrosine

ASJC Scopus subject areas

  • Chemistry(all)

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