Kinetics of ligand substitution reactions in the oxovanadium(IV)-maltol system

Erzsébet Kiss, I. Fábián, T. Kiss

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The kinetics of the complex formation between oxovanadium(IV) and maltol was studied by the stopped-flow method at 25°C in 0.2 M KCl. The formation of the bis-complex is about an order of magnitude faster than that of the mono-complex under the same conditions. The results confirm that parallel paths are operative in these reactions via the acid (HA) and base (A-) forms of the ligand. The relevant rate constants were determined and mechanistic implications of the results are also discussed. It is concluded that the oxovanadium(IV) ion can easily form the thermodynamically most favorable complexes in ligand rich environments such as biological liquids.

Original languageEnglish
Pages (from-to)114-118
Number of pages5
JournalInorganica Chimica Acta
Volume340
DOIs
Publication statusPublished - Nov 25 2002

Fingerprint

Substitution reactions
Ligands
substitutes
ligands
Kinetics
kinetics
Rate constants
Ions
acids
Acids
Liquids
liquids
ions
oxovanadium IV
maltol

Keywords

  • Insulin-mimetic activity
  • Ligand substitution reaction
  • Maltol
  • Oxovanadium(IV) complexes

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Materials Chemistry

Cite this

Kinetics of ligand substitution reactions in the oxovanadium(IV)-maltol system. / Kiss, Erzsébet; Fábián, I.; Kiss, T.

In: Inorganica Chimica Acta, Vol. 340, 25.11.2002, p. 114-118.

Research output: Contribution to journalArticle

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AB - The kinetics of the complex formation between oxovanadium(IV) and maltol was studied by the stopped-flow method at 25°C in 0.2 M KCl. The formation of the bis-complex is about an order of magnitude faster than that of the mono-complex under the same conditions. The results confirm that parallel paths are operative in these reactions via the acid (HA) and base (A-) forms of the ligand. The relevant rate constants were determined and mechanistic implications of the results are also discussed. It is concluded that the oxovanadium(IV) ion can easily form the thermodynamically most favorable complexes in ligand rich environments such as biological liquids.

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