Kinetic studies on the calcium-dependent potassium transport in human red blood cells

A. Schubert, B. Sarkadi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The kinetics of the Ca-dependent K transport across the human red cell membrane were studied under experimental conditions allowing the separation of this step from the previous membrane events. Net potassium and tracer potassium fluxes were measured and a self-consistent model was constructed for calculating the ionic permeability values. All the experimental results could be interpreted by means of a nonsaturable neutral K selective channel. In net K efflux measurements the accompanying Cl movement was found to be rate-limiting and the charge-carrying Cl permeability of the red cell membrane could be calculated.

Original languageEnglish
Pages (from-to)207-216
Number of pages10
JournalActa Biochimica et Biophysica Academiae Scientiarum Hungaricae
Volume12
Issue number3
Publication statusPublished - Dec 1 1977

ASJC Scopus subject areas

  • Medicine(all)

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