During post mortem and histo-pathological examination in a flock infected by highly pathogenic (H5N1 subtype) avian influenza virus strain in 2006, in most of the cases, lesions typical to highly pathogenic avian influenza virus were detected. However in an 11-weeks-old Mulard duck flock of 10 000 animals kidney damage (acute tubulonephrosis) and gout were observed consistently. In the diseased animais neurological signs (deviation of the head and neck, head tremor, ataxia, paralysis) and lymphocytic encephalitis were detected. There were no changes in the pancreas and respiratory system. The examined characteristics and partial sequence data of the H5N1 virus strain isolated from the case were not different from the other H5N1 isolates found at the same time. By immunohistochemical method the virus antigen was detected only from some animals and mainly in small quantity in the spleen, lung, trachea and brain. Keeping conditions and quality of feeding-stuff have not explained the development of kidney damage and gout. In the other mulard ducks kept elsewhere and diseased and died of H5N1 virus infection no kidney damage and gout accompanied the typical lesions characteristic to the acute form of avian influenza. In the birds died in the examined flock Polyomavirus infection was excluded by PCR method.
|Number of pages||7|
|Journal||Magyar Allatorvosok Lapja|
|Publication status||Published - Dec 1 2007|
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