Kallmann's syndrome

Pregnancy through intracytoplasmic sperm injection and complicated by gestational diabetes

A. Szilágyi, Z. Mánfai, L. Kiesel, I. Szabó

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Kallmann's syndrome is characterized by hypogonadotropic hypogonadism and anosmia. Assisted reproductive techniques such as intracytoplasmic sperm injection (ICSI) may be required to treat the infertile couple with oligozoospermia. Rare complications have been described in patients with Kalhnann's syndrome, but gestational diabetes has not previously been reported. A case of Kalhnann's syndrome with infertility is reported. Ovulation teas successfully induced by human menopausal gonadotropin therapy, but pregnancy could not be achieved by artificial insemination or by conventional in vitro fertilization, although the husband had only moderate oligozoospermia. A high fertilization rate of the retrieved oocytes and successful pregnancy was achieved by ICSI. The pregnancy was complicated by gestational diabetes that was managed by insulin therapy. Succesful ovulation induction in Kallmann's syndrome is not rare, but ICSI may be needed in selected cases. Some recent data have suggested that diabetes may occur in patients with Kalhnann's syndrome, but further investigation is needed to establish whether gestational diabetes is associated with Kallmann's syndrome or is purely coincidental.

Original languageEnglish
Pages (from-to)325-327
Number of pages3
JournalGynecological Endocrinology
Volume15
Issue number5
Publication statusPublished - 2001

Fingerprint

Kallmann Syndrome
Intracytoplasmic Sperm Injections
Gestational Diabetes
Oligospermia
Pregnancy
Menotropins
Artificial Insemination
Assisted Reproductive Techniques
Ovulation Induction
Tea
Fertilization in Vitro
Ovulation
Spouses
Fertilization
Infertility
Oocytes
Insulin
Therapeutics

Keywords

  • Diabetes
  • ICSI
  • Kallmann's syndrome
  • Pregnancy

ASJC Scopus subject areas

  • Endocrinology
  • Obstetrics and Gynaecology

Cite this

Kallmann's syndrome : Pregnancy through intracytoplasmic sperm injection and complicated by gestational diabetes. / Szilágyi, A.; Mánfai, Z.; Kiesel, L.; Szabó, I.

In: Gynecological Endocrinology, Vol. 15, No. 5, 2001, p. 325-327.

Research output: Contribution to journalArticle

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