K cell activity is low in newborn infants

P. Siklos, P. Hercz, G. Ringwald, L. Ungar, T. Garam, T. Bakacs

Research output: Contribution to journalArticle


K cell activity of 18 mature, healthy newborns was measured against O,Rh(D)-positive erythrocytes, sensitized by anti-D antibodies, in cord and venous blood (later obtained 3-4 days after delivery). 53 healthy women served as controls. Activity was determined as a function of target cell number in the enzyme-like kinetic model of cytotoxicity. It was low in cord blood, increased in venous blood by days 3-4 but it did not reach the level of adults. While cytotoxicity activity of male infants increased significantly from birth to the 3rd-4th day of life, it did not change in female infants. No correlation was found between the weight and K cell activity of newborns.

Original languageEnglish
Pages (from-to)39-43
Number of pages5
JournalGynecologic and Obstetric Investigation
Issue number1
Publication statusPublished - Jan 1 1988

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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    Siklos, P., Hercz, P., Ringwald, G., Ungar, L., Garam, T., & Bakacs, T. (1988). K cell activity is low in newborn infants. Gynecologic and Obstetric Investigation, 26(1), 39-43. https://doi.org/10.1159/000293670