K-cell activity is enhanced intrapartum

P. Siklós, L. Ungár, P. Hercz, K. Tótpál, Á Németh-Csóka, T. Garam

Research output: Contribution to journalArticle

Abstract

The cytotoxic activity of killer (K)-cells was measured against O Rh(D)-positive human erythrocytes sensitized by anti-D antibodies, in 14 women during normal labor and compared with the K-cell activity of 20 pregnant women (in the 37-40th week of pregnancy) and 42 nonpregnant female controls. K-cell activity was determined by the enzyme-like kinetic cytotoxic model, which measured the maximum of killing capacity. Cytotoxic activity was found to be significantly higher intrapartum. Data are compatible with the possibility that immunologic mechanism(s) are contributing to the onset of parturition.

Original languageEnglish
Pages (from-to)133-135
Number of pages3
JournalImmunology letters
Volume13
Issue number3
DOIs
Publication statusPublished - Sep 1986

Keywords

  • K-cell activity
  • human erythrocyte ADCC
  • labor

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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  • Cite this

    Siklós, P., Ungár, L., Hercz, P., Tótpál, K., Németh-Csóka, Á., & Garam, T. (1986). K-cell activity is enhanced intrapartum. Immunology letters, 13(3), 133-135. https://doi.org/10.1016/0165-2478(86)90045-3