Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography

Mihály Károlyi, Bálint Szilveszter, Márton Kolossváry, Csilla Celeng, Andrea Bartykowszki, L. Jermendy, Alexisz Panajotu, Júlia Karády, Béla Merkely, Pál Maurovich-Horvat

Research output: Contribution to journalArticle

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Abstract

Objective To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA). Methods Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software. Results Overall qualitative image quality significantly improved with HIR as compared to FBP, and further improved with IMR (p < 0.01 all). Contrast-to-noise ratios were improved with IMR, compared to HIR and FBP (51.0 [43.5–59.9], 20.3 [16.2–25.9] and 14.0 [11.2–17.7], respectively, all p < 0.01) Overall plaque volumes were lowest with IMR and highest with FBP (121.7 [79.3–168.4], 138.7 [90.6–191.7], 147.0 [100.7–183.6]). Similarly, calcified volumes (>130 HU) were decreased with IMR as compared to HIR and FBP (105.9 [62.1–144.6], 110.2 [63.8–166.6], 115.9 [81.7–164.2], respectively, p < 0.05 all). High-attenuation non-calcified volumes (90–129 HU) yielded similar values with FBP and HIR (p = 0.81), however it was lower with IMR (p < 0.05 both). Intermediate- (30–89 HU) and low-attenuation (<30 HU) non-calcified volumes showed no significant difference (p = 0.22 and p = 0.67, respectively). Conclusions IMR improves image quality of coronary CTA and decreases calcified plaque volumes.

Original languageEnglish
Pages (from-to)83-89
Number of pages7
JournalEuropean Journal of Radiology
Volume87
DOIs
Publication statusPublished - Feb 1 2017

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Coronary Angiography
Computer-Assisted Image Processing
Software
Computed Tomography Angiography

Keywords

  • Atherosclerotic plaque quantification
  • Cardiac imaging techniques
  • Coronary artery disease
  • Coronary CT angiography
  • Image reconstruction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Károlyi, M., Szilveszter, B., Kolossváry, M., Celeng, C., Bartykowszki, A., Jermendy, L., ... Maurovich-Horvat, P. (2017). Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography. European Journal of Radiology, 87, 83-89. https://doi.org/10.1016/j.ejrad.2016.12.012

Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography. / Károlyi, Mihály; Szilveszter, Bálint; Kolossváry, Márton; Celeng, Csilla; Bartykowszki, Andrea; Jermendy, L.; Panajotu, Alexisz; Karády, Júlia; Merkely, Béla; Maurovich-Horvat, Pál.

In: European Journal of Radiology, Vol. 87, 01.02.2017, p. 83-89.

Research output: Contribution to journalArticle

Károlyi, M, Szilveszter, B, Kolossváry, M, Celeng, C, Bartykowszki, A, Jermendy, L, Panajotu, A, Karády, J, Merkely, B & Maurovich-Horvat, P 2017, 'Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography', European Journal of Radiology, vol. 87, pp. 83-89. https://doi.org/10.1016/j.ejrad.2016.12.012
Károlyi M, Szilveszter B, Kolossváry M, Celeng C, Bartykowszki A, Jermendy L et al. Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography. European Journal of Radiology. 2017 Feb 1;87:83-89. https://doi.org/10.1016/j.ejrad.2016.12.012
Károlyi, Mihály ; Szilveszter, Bálint ; Kolossváry, Márton ; Celeng, Csilla ; Bartykowszki, Andrea ; Jermendy, L. ; Panajotu, Alexisz ; Karády, Júlia ; Merkely, Béla ; Maurovich-Horvat, Pál. / Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography. In: European Journal of Radiology. 2017 ; Vol. 87. pp. 83-89.
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abstract = "Objective To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA). Methods Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software. Results Overall qualitative image quality significantly improved with HIR as compared to FBP, and further improved with IMR (p < 0.01 all). Contrast-to-noise ratios were improved with IMR, compared to HIR and FBP (51.0 [43.5–59.9], 20.3 [16.2–25.9] and 14.0 [11.2–17.7], respectively, all p < 0.01) Overall plaque volumes were lowest with IMR and highest with FBP (121.7 [79.3–168.4], 138.7 [90.6–191.7], 147.0 [100.7–183.6]). Similarly, calcified volumes (>130 HU) were decreased with IMR as compared to HIR and FBP (105.9 [62.1–144.6], 110.2 [63.8–166.6], 115.9 [81.7–164.2], respectively, p < 0.05 all). High-attenuation non-calcified volumes (90–129 HU) yielded similar values with FBP and HIR (p = 0.81), however it was lower with IMR (p < 0.05 both). Intermediate- (30–89 HU) and low-attenuation (<30 HU) non-calcified volumes showed no significant difference (p = 0.22 and p = 0.67, respectively). Conclusions IMR improves image quality of coronary CTA and decreases calcified plaque volumes.",
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AU - Kolossváry, Márton

AU - Celeng, Csilla

AU - Bartykowszki, Andrea

AU - Jermendy, L.

AU - Panajotu, Alexisz

AU - Karády, Júlia

AU - Merkely, Béla

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N2 - Objective To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA). Methods Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software. Results Overall qualitative image quality significantly improved with HIR as compared to FBP, and further improved with IMR (p < 0.01 all). Contrast-to-noise ratios were improved with IMR, compared to HIR and FBP (51.0 [43.5–59.9], 20.3 [16.2–25.9] and 14.0 [11.2–17.7], respectively, all p < 0.01) Overall plaque volumes were lowest with IMR and highest with FBP (121.7 [79.3–168.4], 138.7 [90.6–191.7], 147.0 [100.7–183.6]). Similarly, calcified volumes (>130 HU) were decreased with IMR as compared to HIR and FBP (105.9 [62.1–144.6], 110.2 [63.8–166.6], 115.9 [81.7–164.2], respectively, p < 0.05 all). High-attenuation non-calcified volumes (90–129 HU) yielded similar values with FBP and HIR (p = 0.81), however it was lower with IMR (p < 0.05 both). Intermediate- (30–89 HU) and low-attenuation (<30 HU) non-calcified volumes showed no significant difference (p = 0.22 and p = 0.67, respectively). Conclusions IMR improves image quality of coronary CTA and decreases calcified plaque volumes.

AB - Objective To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA). Methods Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software. Results Overall qualitative image quality significantly improved with HIR as compared to FBP, and further improved with IMR (p < 0.01 all). Contrast-to-noise ratios were improved with IMR, compared to HIR and FBP (51.0 [43.5–59.9], 20.3 [16.2–25.9] and 14.0 [11.2–17.7], respectively, all p < 0.01) Overall plaque volumes were lowest with IMR and highest with FBP (121.7 [79.3–168.4], 138.7 [90.6–191.7], 147.0 [100.7–183.6]). Similarly, calcified volumes (>130 HU) were decreased with IMR as compared to HIR and FBP (105.9 [62.1–144.6], 110.2 [63.8–166.6], 115.9 [81.7–164.2], respectively, p < 0.05 all). High-attenuation non-calcified volumes (90–129 HU) yielded similar values with FBP and HIR (p = 0.81), however it was lower with IMR (p < 0.05 both). Intermediate- (30–89 HU) and low-attenuation (<30 HU) non-calcified volumes showed no significant difference (p = 0.22 and p = 0.67, respectively). Conclusions IMR improves image quality of coronary CTA and decreases calcified plaque volumes.

KW - Atherosclerotic plaque quantification

KW - Cardiac imaging techniques

KW - Coronary artery disease

KW - Coronary CT angiography

KW - Image reconstruction

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