Issues and opportunities of stem cell therapy in autoimmune diseases

Research output: Contribution to journalReview article

Abstract

The purpose of regenerative medicine is to restore or enhance the normal function of human cells, tissues, and organs. From a clinical point of view, the use of stem cells is more advantageous than differentiated cells because they can be collected more easily and in larger quantities, their proliferation capacity is more pronounced, they are more resistant in cell culture, their aging is delayed, they are able to form a number of cell lines, and they are able to promote vascularization of tissue carriers. The therapeutic use of stem cells for disease modification, immunomodulation, or regenerative purposes are undoubtedly encouraging, but most studies are still in their early stages, and the clinical results reported are not clear with regard to therapeutic efficacy and potential side effects. Uniform regulation of the clinical application of stem cells is also indispensable for this highly customizable, minimally invasive, individualized therapeutic method to become a successful and safe treatment alternative in many different autoimmune and autoinflammatory disorders.

Original languageEnglish
Pages (from-to)212-221
Number of pages10
JournalWorld Journal of Stem Cells
Volume11
Issue number4
DOIs
Publication statusPublished - Apr 1 2019

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Cell- and Tissue-Based Therapy
Autoimmune Diseases
Stem Cells
Regenerative Medicine
Immunomodulation
Therapeutic Uses
Therapeutics
Cell Culture Techniques
Cell Line

Keywords

  • Autoimmune
  • Autoinflammatory
  • Disease modification
  • Immunomodulation
  • Stem cell therapy

ASJC Scopus subject areas

  • Histology
  • Molecular Biology
  • Genetics
  • Genetics(clinical)
  • Cell Biology

Cite this

Issues and opportunities of stem cell therapy in autoimmune diseases. / Müzes, G.; Sípos, F.

In: World Journal of Stem Cells, Vol. 11, No. 4, 01.04.2019, p. 212-221.

Research output: Contribution to journalReview article

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