A szomatosztatinanalógok izotópdiagnosztikai és terápiás alkalmazása

Translated title of the contribution: Isotope diagnostic and therapeutic applications of somatostatin analogues. Part 1. Brief review of literature and veterinary applications

Mathé Domokos, L. Balogh, Janoki Gyözö

Research output: Contribution to journalArticle

Abstract

The authors studied applicability of somatostatin receptor isotope diagnosis and therapy in the dog - an anticancer treatment already in human clinical use. In the course of this method a peptide molecule is applied to target overexpressed cell surface receptor proteins. Diagnosis and killing of tumour cells is achieved by gamma or beta emitting radioactive isotope atom attached to the peptide. After binding to the receptor the peptide internalizes and radioactivity becomes fixed within the cell. In the first part of a two-piece series the authors give a brief summary of the elements of the method and its veterinary applications.

Original languageHungarian
Pages (from-to)349-354
Number of pages6
JournalMagyar Allatorvosok Lapja
Volume132
Issue number6
Publication statusPublished - Jun 2010

Fingerprint

somatostatin
Somatostatin
Isotopes
isotopes
peptides
therapy dogs
Somatostatin Receptors
therapeutics
Peptides
Peptide Receptors
Cell Surface Receptors
radionuclides
Radioisotopes
Radioactivity
Membrane Proteins
Dogs
cells
receptors
Therapeutics
methodology

ASJC Scopus subject areas

  • veterinary(all)

Cite this

A szomatosztatinanalógok izotópdiagnosztikai és terápiás alkalmazása. / Domokos, Mathé; Balogh, L.; Gyözö, Janoki.

In: Magyar Allatorvosok Lapja, Vol. 132, No. 6, 06.2010, p. 349-354.

Research output: Contribution to journalArticle

Domokos, Mathé ; Balogh, L. ; Gyözö, Janoki. / A szomatosztatinanalógok izotópdiagnosztikai és terápiás alkalmazása. In: Magyar Allatorvosok Lapja. 2010 ; Vol. 132, No. 6. pp. 349-354.
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