Isotope chirality and asymmetric autocatalysis: A possible entry to biological chirality

Béla Barabás, Luciano Caglioti, Károly Micskei, Claudia Zucchi, Gyula Pályi

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Natural-abundance isotopic substitution in isotopically prochiral groups of otherwise achiral molecules can provide stochastically formed enantiomeric excesses which exceed the sensitivity threshold of sensitive asymmetric autocatalytic (Soai-type) reactions. This kind of induction of chirality should be taken into consideration in in vitro model experiments and offer a new kind of entry into primary prebiotic or early biotic enantioselection in the earliest stages of molecular evolution.

Original languageEnglish
Pages (from-to)317-327
Number of pages11
JournalOrigins of Life and Evolution of Biospheres
Volume38
Issue number4
DOIs
Publication statusPublished - Aug 1 2008

Keywords

  • Asymmetric
  • Autocatalysis
  • Biological chirality
  • Chirality by isotopes
  • Isotopes
  • Natural abundance
  • Soai-reaction

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Space and Planetary Science

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