Isomerization of Substituted Tricyclic 4,5-Dihydropyrazoles

T. Lóránd, F. Aradi, A. Szöllösy, G. Tóth, T. Kónya

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The acid and base catalyzed isomerization of some tricyclic 2-pyrazolines with N-Carbamoyl-, N-thiocarbamoyl- and N-phenyl substituents was investigated. Starting from cis or trans 3-H, 3a-H diastereomers, equilibrium mixtures of cis and trans diastereomers were prepared which were separated and subsequently studied by 1H NMR and 13C NMR spectroscopy. A mechanism for the isomerization of the pyrazolines is suggested, supported by a deuterium exchange at C-3a.

Original languageEnglish
Pages (from-to)971-977
Number of pages7
JournalMonatshefte fur Chemie
Volume127
Issue number8-9
Publication statusPublished - 1996

Fingerprint

Isomerization
Deuterium
Nuclear magnetic resonance spectroscopy
Nuclear magnetic resonance
Acids

Keywords

  • H and C NMR spectroscopy
  • Isomerization
  • N-Substituted 2H-benz[g]indazoles

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Isomerization of Substituted Tricyclic 4,5-Dihydropyrazoles. / Lóránd, T.; Aradi, F.; Szöllösy, A.; Tóth, G.; Kónya, T.

In: Monatshefte fur Chemie, Vol. 127, No. 8-9, 1996, p. 971-977.

Research output: Contribution to journalArticle

Lóránd, T, Aradi, F, Szöllösy, A, Tóth, G & Kónya, T 1996, 'Isomerization of Substituted Tricyclic 4,5-Dihydropyrazoles', Monatshefte fur Chemie, vol. 127, no. 8-9, pp. 971-977.
Lóránd, T. ; Aradi, F. ; Szöllösy, A. ; Tóth, G. ; Kónya, T. / Isomerization of Substituted Tricyclic 4,5-Dihydropyrazoles. In: Monatshefte fur Chemie. 1996 ; Vol. 127, No. 8-9. pp. 971-977.
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AU - Kónya, T.

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