Isolation of dsRNA-associated VLPs from the strain Cryptococcus hungaricus CBS 6569

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Abstract

Double-stranded RNAs (dsRNAs) with molecular masses 1.7 and 5.0 kbp, respectively, were isolated from the strain Cryptococcus hungaricus CBS 6569. The dsRNAs were copurified with eicosahedric virus-like particles, 29 nm in diameter. This strain produced a protease-sensitive 'toxin' which inhibited the growth of strain C. hungaricus CBS 4214. The toxin had maximum activity at pH 3.7. The highest toxin amount was attained after a culture period of four days.

Original languageEnglish
Pages (from-to)151-154
Number of pages4
JournalFEMS microbiology letters
Volume162
Issue number1
DOIs
Publication statusPublished - May 1 1998

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Keywords

  • Cryptococcus hungaricus
  • Double-stranded RNA
  • Mycocin
  • Virus-like particle

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology
  • Genetics

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