Szarvasmarha-herpesvirus-4 (BHV-4) izolálása agyvelobol

Translated title of the contribution: Isolation of bovine herpes virus-4 (BHV-4) from the brain of a cattle

Research output: Contribution to journalArticle

Abstract

BHV-4 virus was isolated from the brain of a cattle with nervous symptoms, originating from a back-yard stock. The animal showed incoordination, extremital weakness, then lied down. Histopathological examination of the brain revealed focal gliosis and infiltration by mononuclear cells in the meninx covering the occipital cerebral cortex.The laboratory investigations excluded rabies, IBR and Aujeszky's disease. A slowly growing virus was isolated in MDBK cells that could successfully be further passaged in calf testis and calf kidney cells. Based on the chloroform sensitivity, cytopathogenic effect, morphology of intranuclear inclusion bodies and serological properties, the isolate was identified as BHV-4. This is the first report of the isolation of BHV-4 virus from the brain of a cattle. Further interesting observations are that the animal showed expressed clinical symptoms and histopathological changes of viral origin were found in the brain. The possibility arises that the animal was previously sick and the virus could infect the organism with a diminished presistance. Artificial infection experiment would be necessary to confirm this suggestion.

Original languageHungarian
Pages (from-to)591-593
Number of pages3
JournalMagyar Allatorvosok Lapja
Volume51
Issue number10
Publication statusPublished - 1996

Fingerprint

Viruses
brain
viruses
cattle
Brain
signs and symptoms (animals and humans)
Pseudorabies
nuclear inclusions
calves
meninges
ataxia (disorder)
Intranuclear Inclusion Bodies
Meninges
Occipital Lobe
Aujeszky disease
animals
Gliosis
cytopathogenicity
Rabies
cerebral cortex

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Szarvasmarha-herpesvirus-4 (BHV-4) izolálása agyvelobol. / Hornyák, A.; Pálfi, V.

In: Magyar Allatorvosok Lapja, Vol. 51, No. 10, 1996, p. 591-593.

Research output: Contribution to journalArticle

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