Isolation and on-line LC/CD analysis of 3,8″-linked biflavonoids from Gnidia involucrata

Julien Ferrari, Christian Terreaux, Tibor Kurtán, Attila Szikszai-Kiss, Sándor Antus, Jerome D. Msonthi, Kurt Hostettmann

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Investigation of the methanol extract of the roots of Gnidia involucrata (Thymelaeaceae) led to the isolation and characterization of two new 3,8″-biflavonoid diastereoisomers, named GB-4 (6a) and GB-4a (6b). Their absolute configurations were determined in mixture by on-line LC/CD measurements, which also allowed the revision of absolute configurations of the biflavanoids GB-1 and GB-2, and the configurational assignment of GB-3.

Original languageEnglish
Pages (from-to)2768-2778
Number of pages11
JournalHelvetica Chimica Acta
Volume86
Issue number8
DOIs
Publication statusPublished - Sep 26 2003

ASJC Scopus subject areas

  • Catalysis
  • Biochemistry
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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