Isolation and complete genome characterization of novel reassortant orthoreovirus from common vole (Microtus arvalis)

Enikő Fehér, Gábor Kemenesi, Miklós Oldal, Kornélia Kurucz, Renáta Kugler, Szilvia L. Farkas, Szilvia Marton, Győző Horváth, K. Bányai, F. Jakab

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A novel mammalian orthoreovirus (MRV) strain was isolated from the lung tissue of a common vole (Microtus arvalis) with Tula hantavirus infection. Seven segments (L1–L3, M2–M3, S2, and S4) of the Hungarian MRV isolate MORV/47Ma/06 revealed a high similarity with an MRV strain detected in bank vole (Myodes glareolus) in Germany. The M1 and S3 segment of the Hungarian isolate showed the closest relationship with the sequence of a Slovenian human and a French murine isolate, respectively. The highest nucleotide and amino acid identity values were above 90 and 95% in all of the comparisons to the reference sequences in GenBank, except for the S1 with a maximum of 69.6% nucleotide and 75.4% amino acid identity. As wild rodents are among the main sources of zoonotic infections, the reservoir role of these animals and zoonotic potential of rodent origin MRVs need to be further investigated.

Original languageEnglish
Pages (from-to)307-311
Number of pages5
JournalVirus Genes
Volume53
Issue number2
DOIs
Publication statusPublished - Apr 1 2017

Fingerprint

Orthoreovirus
Arvicolinae
Genome
Zoonoses
Rodentia
Mammalian Orthoreovirus
Nucleotides
Hantavirus Infections
Amino Acids
Nucleic Acid Databases
Germany
Lung

Keywords

  • Common vole
  • Hungary
  • Orthoreovirus
  • Reassortant

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Virology

Cite this

Isolation and complete genome characterization of novel reassortant orthoreovirus from common vole (Microtus arvalis). / Fehér, Enikő; Kemenesi, Gábor; Oldal, Miklós; Kurucz, Kornélia; Kugler, Renáta; Farkas, Szilvia L.; Marton, Szilvia; Horváth, Győző; Bányai, K.; Jakab, F.

In: Virus Genes, Vol. 53, No. 2, 01.04.2017, p. 307-311.

Research output: Contribution to journalArticle

Fehér, E, Kemenesi, G, Oldal, M, Kurucz, K, Kugler, R, Farkas, SL, Marton, S, Horváth, G, Bányai, K & Jakab, F 2017, 'Isolation and complete genome characterization of novel reassortant orthoreovirus from common vole (Microtus arvalis)', Virus Genes, vol. 53, no. 2, pp. 307-311. https://doi.org/10.1007/s11262-016-1411-1
Fehér, Enikő ; Kemenesi, Gábor ; Oldal, Miklós ; Kurucz, Kornélia ; Kugler, Renáta ; Farkas, Szilvia L. ; Marton, Szilvia ; Horváth, Győző ; Bányai, K. ; Jakab, F. / Isolation and complete genome characterization of novel reassortant orthoreovirus from common vole (Microtus arvalis). In: Virus Genes. 2017 ; Vol. 53, No. 2. pp. 307-311.
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