Isoform specific expression of Δ9 desaturases in two brain regions of common carp

Beáta Balla, Edit Hermesz

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

An appropriate ratio of saturated and unsaturated fatty acids contributes to membrane fluidity. The Δ9 stearoyl-CoA desaturases are key enzymes involved in the regulation of the lipid composition of cellular membranes. The expressions of the Δ9 stearoyl-CoA desaturase genes are regulated by many environmental factors, such as temperature changes and metal exposure, mostly at the levels of transcription and mRNA stability. The present study analyzes the effects of cold shock and Cd2+ treatment on the regulation of two Δ9 desaturase genes in the olfactory lobe and the cerebellum of common carp. The effect of Cd2+ was also followed on the expressions of the Δ9 desaturase genes of cold-shocked animals. Sudden cold shock or Cd 2+ exposure induced Δ9 desaturase expressions in a time-, brain region- and isoform-specific manner. In contrast, both Δ9 desaturase genes were repressed by Cd2+ in cold-shocked animals.

Original languageEnglish
Pages (from-to)29-33
Number of pages5
JournalActa Biologica Szegediensis
Volume53
Issue numberSUPPL. 1
Publication statusPublished - Dec 1 2009

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Keywords

  • Brain
  • Carp
  • Cold
  • Desaturase
  • Heavy metal
  • Shock
  • Δ9

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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