ISOCRATIC REVERSED PHASE LIQUID CHROMATOGRAPHIC SEPARATION OF INSULINS.

Z. Varga-Puchony, E. Hites-Papp, J. Hlavay, Gy Vigh

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A simple, isocratic liquid chromatographic separation method was developed for the analysis of bovine and porcine insulins and their desamido decomposition products. The dependence of insulin retention upon the water concentration of the eluent and the chain-length of the tetraalkyl ammonium ion pair reagents was investigated. The applicability of the system for routine production control purposes was demonstrated by the analysis of crude insulin samples and a monocomponent insulin preparation.

Original languageEnglish
Pages (from-to)339-346
Number of pages8
JournalHungarian Journal of Industrial Chemistry
Volume9
Issue number4
Publication statusPublished - Jan 1 1981

    Fingerprint

ASJC Scopus subject areas

  • Chemistry (miscellaneous)
  • Chemistry(all)
  • Chemical Engineering(all)

Cite this