A simple, isocratic liquid chromatographic separation method was developed for the analysis of bovine and porcine insulins and their desamido decomposition products. The dependence of insulin retention upon the water concentration of the eluent and the chain-length of the tetraalkyl ammonium ion pair reagents was investigated. The applicability of the system for routine production control purposes was demonstrated by the analysis of crude insulin samples and a monocomponent insulin preparation.
|Number of pages||8|
|Journal||Hungarian Journal of Industrial Chemistry|
|Publication status||Published - Jan 1 1981|
ASJC Scopus subject areas
- Chemistry (miscellaneous)
- Chemical Engineering(all)