Is there a difference in Doppler myocardial imaging-pulsed Doppler spectrum between acute and chronic myocardial ischemia?

I. Hegedus, L. Voith, A. Peter, Z. Koszegi, I. Édes

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Abstract

Doppler myocardial imaging is a new echocardiographic technique allowing the visualization of moving myocardial segment velocity in all phases of systole and diastole. The aim of this study was to examine the characteristics of Doppler myocardial imaging-pulsed Doppler spectrum of human hearts in acute and chronic ischemia. Acute ischemia was provoked during percutaneous transluminal coronary angioplasty by balloon inflation. The hibernated (chronic ischemic) segments were selected by normal 18-fluorodesoxyglucose uptake on positron emission tomography and 99mTc-MIBI SPECT. Isovolumic contraction velocity, peak systolic velocity, late contraction velocity, and early and late diastolic velocities were examined in both acute ischemic (during left anterior descending branch coronary angioplasty of 19 patients) and chronically ischemic hibernated (23 patients) segments. The control group consisted of 18 patients who underwent coronary angiography, but did not have significant coronary stenosis. Isovolumic contraction velocity was significantly higher in hibernated segments than in controls (11.5 ± 1.9 vs 6.3 ± 1.1 cm/s). On the other hand, as compared to controls, peak systolic velocity was significantly lower in hibernated segments. In acute ischemic segments, a high-amplitude late systolic contraction wave appeared (45.6 ± 14.3 cm/s). Coronary angioplasty-induced ischemia resulted in a significant decrease in early diastolic velocity, while late diastolic velocity significantly increased. Acute ischemia-related alterations in both systolic and diastolic velocities were reversible within 24 hours. In conclusion, Doppler myocardial imaging is a useful technique to distinguish between acute and chronic ischemic myocardial wall segments; the high isovolumic contraction velocity is characteristic of hibernated myocardial segments; the appearance of a high-amplitude late systolic contraction wave is characteristic of acute ischemia.

Original languageEnglish
Pages (from-to)33-37
Number of pages5
JournalCardiovascular Imaging
Volume11
Issue number1
Publication statusPublished - 1999

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Myocardial Ischemia
Ischemia
Angioplasty
Diastole
Coronary Balloon Angioplasty
Systole
Coronary Stenosis
Economic Inflation
Single-Photon Emission-Computed Tomography
Coronary Angiography
Positron-Emission Tomography
Control Groups

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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Is there a difference in Doppler myocardial imaging-pulsed Doppler spectrum between acute and chronic myocardial ischemia? / Hegedus, I.; Voith, L.; Peter, A.; Koszegi, Z.; Édes, I.

In: Cardiovascular Imaging, Vol. 11, No. 1, 1999, p. 33-37.

Research output: Contribution to journalArticle

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