Is the sclerotic vessel wall really more rigid than the normal one?

G. Márk, A. G. Hudetz, T. Kerényi, E. Monos, A. G. Kovách

Research output: Contribution to journalArticle

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Abstract

Quasistatic passive mechanical properties of fibrosclerotic and normal human anterior cerebral arteries were studied in vitro. Mechanical properties were characterized by incremental elastic modulus, strain energy density and incremental distensibility for a 20--250 mm Hg intraluminal pressure range. Fibrotic arteries were found to have a 34--45% lower elastic modulus at the same pressure levels than normal ones (p less than 0.01--0.02). Distensibility however proved to be only 28--35% higher in the fibrotic group, this difference was significant just at a few pressure values above 120 mm Hg. This was due to the opposite changes in elastic properties and radius to wall thickness ratio. It is supposed that higher elasticity of the fibrotic arterial wall is the consequence of a local compensatory process tending to prevent pathological alterations in distensibility of the arteries.

Original languageEnglish
Pages (from-to)292-297
Number of pages6
JournalProgress in biochemical pharmacology
Volume13
Publication statusPublished - 1977

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Elastic Modulus
Pressure
Arteries
Anterior Cerebral Artery
Elasticity
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Márk, G., Hudetz, A. G., Kerényi, T., Monos, E., & Kovách, A. G. (1977). Is the sclerotic vessel wall really more rigid than the normal one? Progress in biochemical pharmacology, 13, 292-297.

Is the sclerotic vessel wall really more rigid than the normal one? / Márk, G.; Hudetz, A. G.; Kerényi, T.; Monos, E.; Kovách, A. G.

In: Progress in biochemical pharmacology, Vol. 13, 1977, p. 292-297.

Research output: Contribution to journalArticle

Márk, G, Hudetz, AG, Kerényi, T, Monos, E & Kovách, AG 1977, 'Is the sclerotic vessel wall really more rigid than the normal one?', Progress in biochemical pharmacology, vol. 13, pp. 292-297.
Márk, G. ; Hudetz, A. G. ; Kerényi, T. ; Monos, E. ; Kovách, A. G. / Is the sclerotic vessel wall really more rigid than the normal one?. In: Progress in biochemical pharmacology. 1977 ; Vol. 13. pp. 292-297.
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