Is the saccharide component of the insulin receptor involved in hormonal imprinting?

P. Kovacs, G. Csaba

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Hormonal imprinting takes place at the first interaction of a given hormone with the cell (the Tetrahymena in the present case) and accounts for a greater responsiveness to the hormone on re-exposure(s). The Tetrahymena is able to bind insulin and Concanavalin-A (Con-A) as well. Exposure to both ligands - simultaneously or in sequence - enhances the binding of both in the progeny generations. It follows that the lectin, which inhibits insulin binding by direct action, enhances rather than depresses the effect of insulin-induced imprinting.

Original languageEnglish
Pages (from-to)111-114
Number of pages4
JournalCell Biochemistry and Function
Volume4
Issue number2
Publication statusPublished - 1986

Fingerprint

Insulin Receptor
Tetrahymena
Insulin
Hormones
Concanavalin A
Lectins
Ligands

ASJC Scopus subject areas

  • Cell Biology
  • Clinical Biochemistry

Cite this

Is the saccharide component of the insulin receptor involved in hormonal imprinting? / Kovacs, P.; Csaba, G.

In: Cell Biochemistry and Function, Vol. 4, No. 2, 1986, p. 111-114.

Research output: Contribution to journalArticle

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